Gadolinium-based contrast agents and NSF: evidence from animal experience

Journal of Magnetic Resonance Imaging : JMRI
Martin A SieberHubertus Pietsch

Abstract

Nephrogenic systemic fibrosis (NSF) is a potentially severe systemic disease typically characterized by fibrosis of the skin and connective tissues. The etiology of NSF is still unknown but is likely to be multifactorial. Specific triggers under scientific evaluation have included surgery and/or the occurrence of thrombosis or other vascular injury, proinflammatory state, the administration of high doses of erythropoietin, and more recently the use of gadolinium-based contrast agents (GBCAs). The aim of this review is to summarize knowledge regarding the pathogenesis of NSF and the potential role of GBCAs in its pathology, with a focus on animal experiments. The potential role of complex stability of GCBAs will be highlighted by results from several in vitro and in vivo experiments in rodent models of NSF. J. Magn. Reson. Imaging 2009;30:1268-1276. (c) 2009 Wiley-Liss, Inc.

References

Jan 1, 1992·Magnetic Resonance Imaging·P WedekingM F Tweedle
May 1, 1991·Cancer Causes & Control : CCC·M T Goodman, L R Wilkens
Nov 1, 1991·Investigative Radiology·G Schuhmann-Giampieri, G Krestin
Jan 1, 1991·Magnetic Resonance Imaging·M F TweedleC A Chang
Jan 1, 1990·Magnetic Resonance Imaging·W P CacherisS M Rocklage
Jul 1, 1989·Medical Hypotheses·R A Evans
Jan 1, 1988·International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology·P Wedeking, M Tweedle
Mar 1, 1988·Risk Analysis : an Official Publication of the Society for Risk Analysis·C C Travis, R K White
Oct 10, 2006·Journal of Cutaneous Pathology·Kevan G LewisLeslie Robinson-Bostom
Dec 29, 2006·Contrast Media & Molecular Imaging·Sophie LaurentRobert N Muller
Mar 3, 2007·The Journal of Clinical Investigation·John Varga, David Abraham
May 8, 2007·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Peter MarckmannHenrik S Thomsen
Aug 21, 2007·The British Journal of Radiology·H Schmitt-Willich
Aug 23, 2007·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·I M WahbaK White
Jan 9, 2008·Journal of the American College of Radiology : JACR·Richard Bucala
Mar 18, 2008·European Journal of Radiology·Henrik S Thomsen, Peter Marckmann
Mar 25, 2008·European Journal of Radiology·Marie-France Bellin, Aart J Van Der Molen
Apr 1, 2008·European Journal of Radiology·Jerrold L Abraham, Charu Thakral
Aug 9, 2008·Nephron. Clinical Practice·S K Morcos, H S Thomsen
Aug 20, 2008·Radiology·Martin R PrinceAnthony M Valeri
Nov 13, 2008·Investigative Radiology·Thomas FrenzelHanns-Joachim Weinmann
Jan 10, 2009·Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Für Toxikologische Pathologie·T Steger-HartmannJ Walter
Jul 25, 2009·Journal of Magnetic Resonance Imaging : JMRI·Hubertus PietschMartin A Sieber

❮ Previous
Next ❯

Citations

Sep 15, 2012·Toxicological Sciences : an Official Journal of the Society of Toxicology·Nathalie FretellierClaire Corot
Jan 27, 2016·Advances in Therapy·Jessica LohrkeHubertus Pietsch
Feb 12, 2013·Journal of Controlled Release : Official Journal of the Controlled Release Society·M HowellS Mohapatra
Jul 26, 2011·Seminars in Nephrology·Richard N Hellman
May 3, 2011·Advances in Chronic Kidney Disease·Ali K Abu-Alfa
Sep 23, 2010·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Dipanjan PanGregory M Lanza
Sep 11, 2010·Contrast Media & Molecular Imaging
Nov 26, 2009·Journal of Magnetic Resonance Imaging : JMRI·Tim Leiner, Walter Kucharczyk
Feb 4, 2012·Journal of the American College of Cardiology·Karen C Briley-SaeboSotirios Tsimikas
Dec 30, 2014·PloS One·Christian RosenbergNorbert Hosten
Aug 18, 2016·Magnetic Resonance Imaging·Richard C SemelkaMiguel Ramalho
Feb 17, 2015·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Elizabeth J BrisboisHitesh Handa
Jul 22, 2017·Journal of Magnetic Resonance Imaging : JMRI·Simona BussiFederico Maisano
Sep 27, 2018·Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes·Andreu F CostaNicola Schieda
Feb 28, 2014·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Nipon PothayeeJ S Riffle
Apr 15, 2017·Pediatric Radiology·Eric M GaleMichael S Gee
Jun 28, 2016·Journal of Materials Chemistry. B, Materials for Biology and Medicine·X W LiJ L Shi
Feb 28, 2015·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Changqiang WuHua Ai
Oct 17, 2020·Dalton Transactions : an International Journal of Inorganic Chemistry·Duraiyarasu MaheshwaranRamasamy Mayilmurugan
Oct 24, 2018·Chemical Reviews·Jessica WahsnerPeter Caravan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.