PMID: 2503770Aug 1, 1989Paper

Gadolinium-DTPA-enhanced magnetic resonance imaging in intractable partial epilepsy

Neurology
G D CascinoF W Sharbrough

Abstract

We performed magnetic resonance imaging (MRI), before and after the administration of gadolinium-DTPA (Gd-DTPA), in 23 patients with medically refractory partial epilepsy who subsequently had surgical treatment for their seizure disorder. In most patients, 61%, unenhanced and enhanced MRI studies were negative. In 26% the unenhanced image was positive, and the abnormality enhanced with Gd-DTPA. In 13% the unenhanced MR image was positive, but the abnormality did not enhance with Gd-DTPA. Gd-DTPA does not appear to increase the diagnostic yield of MRI in the presurgical evaluation of patients with partial epilepsy if the unenhanced MRIs are normal.

Citations

Jan 1, 1993·Journal of Magnetic Resonance Imaging : JMRI·S M Rocklage, A D Watson
Apr 30, 1998·Journal of Magnetic Resonance Imaging : JMRI·Y Y Sitoh, R D Tien
Dec 1, 1990·Mayo Clinic Proceedings·G D Cascino
Nov 21, 2002·Mayo Clinic Proceedings·Elson L So
Nov 22, 1990·The New England Journal of Medicine·M L Scheuer, T A Pedley
Sep 1, 2003·Journal of Clinical Neuromuscular Disease·Scott Pearlman, Rahman Pourmand
Mar 14, 2020·Current Neurology and Neuroscience Reports·Ayushe A Sharma, Jerzy P Szaflarski

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