Galanin immunoreactivity in autonomic innervation of the cat eye

The Journal of Comparative Neurology
P A GrimesR A Stone

Abstract

In an immunohistochemical study, we find that galanin is much more widely distributed in the peripheral innervation of the cat eye than in other animals so far examined. Previous studies of rat and pig eyes have revealed sparse galanin-positive nerves that presumably originate in the trigeminal ganglion. In contrast, the cat has a rich supply of galanin-containing nerve fibers throughout the uvea. Galanin-positive varicose nerves concentrate densely in iris muscles and distribute more sparsely in the ciliary muscle. The ciliary processes have a plexus of galanin-positive nerves underlying the ciliary epithelium at their base and positive nerve fibers coursing within their stroma. The ciliary artery and its branch vessels in the uvea are invested with a dense plexus of galanin-positive nerves. All autonomic ganglia supplying the eye contain cells that express galanin. It is present in 97% of superior cervical ganglion cells, coexisting with both tyrosine hydroxylase and neuropeptide Y; in 80% of pterygopalatine ganglion cells, most of which also contain vasoactive intestinal peptide; and in approximately 25% of ciliary ganglion cells. After unilateral superior cervical ganglionectomy, galanin-positive nerves almost totally disap...Continue Reading

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Citations

Jul 8, 2010·Histochemistry and Cell Biology·Karin StübingerFalk Schrödl
Oct 11, 2003·Experimental Eye Research·Kazutsuna YamajiShiro Usui
Nov 19, 2013·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Najam A SharifDorette Ellis
Jul 29, 2006·Brain Research Reviews·Josef TrogerEduard Schmid
Jul 19, 2002·Experimental Eye Research·Sally I FirthDavid W Marshak
Jul 1, 2015·Experimental Eye Research·Falk SchrödlHerbert A Reitsamer
May 27, 1999·Vision Research·J M RamírezJ García-Sánchez
Mar 22, 2003·European Journal of Oral Sciences·Michael A BaumannHannsjörg Schröder

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