Galectin expression in healing wounded skin treated with low-temperature plasma: Comparison with treatment by electronical coagulation

Archives of Biochemistry and Biophysics
Yoshihiro AkimotoYuzuru Ikehara

Abstract

Low-temperature plasma is useful for the care of wounded skin. It accelerates wound healing. However, the mechanism of this effect has not been fully elucidated yet. Galectin-1 is reported to accelerate wound healing via the Smad signaling pathway. In the present study to clarify whether or not galectins were expressed during the process of wound healing in the plasma-treated skin, we examined the effect of low-temperature plasma on galectin expression in the healing skin. We compared the effects of low-temperature plasma on the expression of galectin-1, -2, and -3 in the healing skin with those of electrocoagulation conducted with a high-frequency electrical coagulator. Immediately after the start of low-temperature plasma treatment following the incision made in the skin, a membrane-like structure was formed on the surface of the wound. Immunoelectron microscopy showed that these galectins were localized in the membrane-like structure of the plasma-treated skin. The expressions of these galectins were increased by the low-temperature plasma treatment, whereas they were inhibited by the electrocoagulation. These results suggest that galectins were involved in the wound healing of low-temperature plasma-treated skin. Galectins ...Continue Reading

References

Oct 3, 2008·Molecular Biology of the Cell·Gaëlle GendronneauFrançoise Poirier
Mar 3, 2012·The Review of Scientific Instruments·H SakakitaY Sato
Sep 15, 2012·Cell Biology International·Beate HaertelUlrike Lindequist
Jan 8, 2013·Expert Opinion on Therapeutic Targets·Karel SmetanaHans-Joachim Gabius
Feb 6, 2014·PloS One·Suhail Al-Salam, Satwat Hashmi
May 15, 2015·Journal of Wound Care·C UlrichB Lange-Asschenfeldt

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Citations

Mar 28, 2017·Reviews in the Neurosciences·Bastien Paré, François Gros-Louis
Jul 26, 2018·Biological Chemistry·Nagendra Kumar KaushikEun Ha Choi
Oct 7, 2018·Biological Chemistry·Hiromasa TanakaMasaru Hori
Feb 7, 2017·Journal of Clinical Biochemistry and Nutrition·Hiromasa Tanaka, Masaru Hori
Aug 4, 2019·Scientific Reports·Takashi YamaguchiYuzuru Ikehara

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