Gamma-Band Modulation and Coherence in the EEG by Involuntary Eye Movements in Patients in Unresponsive Wakefulness Syndrome

Clinical EEG and Neuroscience
Susanne BalazsI Bodis-Wollner

Abstract

Gamma power and coherence in the electroencephalogram increase in healthy individuals in association with voluntary eye movements, saccades. Patients with unresponsive wakefulness syndrome show repetitive involuntary eye movements that are similar to saccades but progress at a much lower speed. In the present study, we explored the changes in gamma power and coherence related to these eye movements and investigated whether any relationship to the patients' clinical status could be found that would indicate first neurophysiological signs of recovery. To this end, we assessed the clinical status and registered classical scalp electroencephalography with 19 surface electrodes and electro-oculogram of 45 consecutive patients at admission and at 4 weekly intervals. Slow gamma activity (in the frequency range of 37-40 Hz) was analyzed before, during, and after eye movements (pre, -intra and post-eye movement) by means of "continuous wavelet transform." We graded recovery using clinical behavioral scales, taking into account the variables, age, gender, recovery (yes or no), as well as the patients diagnoses (traumatic brain injury, hypoxia, hemorrhage, infection). Statistical evaluation was performed using DataLab, R, and Kruskal-Wall...Continue Reading

References

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Apr 19, 2002·Annals of the New York Academy of Sciences·I Bodis-WollnerM Sabet
Apr 4, 2006·Journal of the Neurological Sciences·Susanne BalazsIvan Bodis-Wollner
May 12, 2007·Cerebral Cortex·Csaba RajkaiCharles E Schroeder
Dec 20, 2007·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Vidya P KulkarniSelim R Benbadis
May 22, 2008·Perception·Peter B ForgacsIvan Bodis-Wollner
May 22, 2008·Perception·Ivan Bodis-Wollner
Nov 3, 2010·BMC Medicine·Steven LaureysUNKNOWN European Task Force on Disorders of Consciousness

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Citations

Jan 1, 2018·Multisensory Research·G Vinodh KumarArpan Banerjee

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Software Mentioned

DataLab
SBEM )
R

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