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Gamma interferon-producing CD4+ T lymphocytes in the lung correlate with resistance to infection with Mycobacterium tuberculosis

Infection and Immunity

Mar 20, 2001

Alissa ChackerianSamuel M Behar

Abstract

The human immune system efficiently limits the replication of Mycobacterium tuberculosis in most infected individuals. Only 5 to 10% of infected people develop clinical tuberculosis, a sign of the inability of the immune system to control the infection. We have studied the C3H/HeJ (C3H)...read more

Mentioned in this Paper

Immune Response
Immune System
T-Lymphocyte
IFNG
TLR4 gene
Edodekin Alfa
Lung
Tuberculosis
C57BL/6 Mouse
Spleen
Paper Details
References
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  • Citations83
123
  • References25
  • Citations83
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Gamma interferon-producing CD4+ T lymphocytes in the lung correlate with resistance to infection with Mycobacterium tuberculosis

Infection and Immunity

Mar 20, 2001

Alissa ChackerianSamuel M Behar

PMID: 11254633

DOI: 10.1128/iai.69.4.2666-2674.2001

Abstract

The human immune system efficiently limits the replication of Mycobacterium tuberculosis in most infected individuals. Only 5 to 10% of infected people develop clinical tuberculosis, a sign of the inability of the immune system to control the infection. We have studied the C3H/HeJ (C3H)...read more

Mentioned in this Paper

Immune Response
Immune System
T-Lymphocyte
IFNG
TLR4 gene
Edodekin Alfa
Lung
Tuberculosis
C57BL/6 Mouse
Spleen

Feeds With Similar Papers

American Thoracic Society: Allergy, Immunology & Inflammation

This feed has been developed in conjunction with the American Thoracic Society for the benefit of its Allergy, Immunology, and Inflammation Assembly. It highlights new and impactful papers on allergy, asthma, genetics, and the pathogenesis of lung diseases.

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Paper Details
References
  • References25
  • Citations83
123
  • References25
  • Citations83
12345...

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