Abstract
The purpose of this report is to present long-term outcomes of gamma knife radiosurgery for intracranial mature teratoma after debulking surgery. Three patients with intracranial mature teratoma had initial target volumes of 5.4, 18.7, and 5.1 cm(3), respectively, and were treated by gamma knife radiosurgery between 1993 and 2004. Marginal doses of 17, 12.5, and 13.5 Gy, respectively, were delivered to the tumors at isodose levels of 50%, 50%, and 62%, respectively. The first patient received radiosurgery after surgical removal and conventional radiotherapy. The second patient received similar management, including surgery and radiotherapy, with tumor recurrence. Two additional operations and subsequent radiosurgery were performed on this patient. Based on the favorable results of the first 2 patients, we performed radiosurgery instead of conventional radiotherapy after subtotal surgical removal in the last patient. By reviewing literatures concerning the therapeutic modalities and the long-term results of our 3 patients, we discuss the role of radiosurgery in treating intracranial mature teratoma. A follow-up period of 121, 89, and 31 months, respectively, demonstrated tumor volume reduction rates of 70%, 89%, and 48%, respect...Continue Reading
References
Sep 15, 1992·Cancer·D M Ho, H C Liu
Nov 1, 1990·Surgical Neurology·S J HuntH W Pittman
May 1, 1988·Journal of Neurosurgery·M S EdwardsW M Wara
Aug 1, 1985·Journal of Neurosurgery·M T JenningsF Hochberg
Sep 1, 1987·Neurosurgery·A J DrapkinM B Pellmar
Jun 1, 1988·Cancer·C R KershR D Marks
Feb 1, 1969·Helvetica paediatrica acta·A Moragas, M T Vidal
Mar 1, 1997·Journal of Neurosurgery·M MatsutaniT Seto
Apr 21, 1998·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·B K ChoK S Choi
Oct 23, 1998·Stereotactic and Functional Neurosurgery·W Y ChungL S Lee
Feb 9, 1999·Journal of Neurosurgery·K Sano
Apr 20, 1999·Pediatric Neurology·D L KeeneE Ventureyra
Feb 14, 2002·Neurosurgery·Keiji SugimotoMichio Nishikawa
Feb 28, 2002·Neurosurgery·P Steinbok
Nov 1, 1946·Journal of Neurosurgery·F D INGRAHAM, O T BAILEY
Citations
May 1, 2009·Acta neurochirurgica·Aliasgar MoiyadiS V Kane
Nov 4, 2008·Journal of Neurosurgery. Pediatrics·Rémy NoudelPascal Rousseaux
Oct 28, 2011·Neuro-Chirurgie·O CoulibalyF Bellakhdar
Jan 17, 2017·Acta neurochirurgica·Carlito LagmanIsaac Yang
Dec 23, 2011·Journal of Child Neurology·Qiang LiJianguo Xu
Jun 10, 2021·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Andrea FranziniPiero Picozzi
Nov 2, 2021·Neuro-oncology·D FrappazE Bouffet