Gamma knife radiosurgery for intracranial mature teratoma--long-term results and review of literature

Surgical Neurology
Cheng-Di ChiuLiang-Shong Lee

Abstract

The purpose of this report is to present long-term outcomes of gamma knife radiosurgery for intracranial mature teratoma after debulking surgery. Three patients with intracranial mature teratoma had initial target volumes of 5.4, 18.7, and 5.1 cm(3), respectively, and were treated by gamma knife radiosurgery between 1993 and 2004. Marginal doses of 17, 12.5, and 13.5 Gy, respectively, were delivered to the tumors at isodose levels of 50%, 50%, and 62%, respectively. The first patient received radiosurgery after surgical removal and conventional radiotherapy. The second patient received similar management, including surgery and radiotherapy, with tumor recurrence. Two additional operations and subsequent radiosurgery were performed on this patient. Based on the favorable results of the first 2 patients, we performed radiosurgery instead of conventional radiotherapy after subtotal surgical removal in the last patient. By reviewing literatures concerning the therapeutic modalities and the long-term results of our 3 patients, we discuss the role of radiosurgery in treating intracranial mature teratoma. A follow-up period of 121, 89, and 31 months, respectively, demonstrated tumor volume reduction rates of 70%, 89%, and 48%, respect...Continue Reading

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Citations

Nov 4, 2008·Journal of Neurosurgery. Pediatrics·Rémy NoudelPascal Rousseaux
Jun 10, 2021·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Andrea FranziniPiero Picozzi

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