Gamma Knife radiosurgery for the treatment of brainstem tumors

Stereotactic and Functional Neurosurgery
M HiratoY Andou

Abstract

Ten patients with brainstem tumors (BST) underwent Gamma Knife radiosurgery. In 5 cases, there were definitive histological diagnoses; ependymoma (n = 3) and CNS lymphoma (n = 2). The others were diagnosed as ependymoma (n = 1), CNS lymphoma (n = 2) and glioma (n = 2) on clinical grounds. Of 4 cases with ependymoma, the tumor showed a marked response in 3 cases. Of 4 cases with CNS lymphoma, all responded rapidly and the clinical symptoms improved markedly. However, in the 2 cases with glioma, the tumor remained unchanged or continued to grow. Gamma Knife radiosurgery was effective in local growth control of BST without adverse effects. An alternative treatment design will be required in glioma cases.

Citations

Jun 5, 2003·Current Opinion in Oncology·Massimo GerosaRoberto Foroni
Jan 24, 2007·Journal of Neurosurgery·Chun Po YenLadislau Steiner
Jun 5, 2004·British Journal of Neurosurgery·S CagliE Demirtas
Apr 10, 2009·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Mark D Krieger, J Gordon McComb
Feb 5, 2009·Neurosurgery·Hideyuki KanoL Dade Lunsford
Dec 17, 2014·Acta neurochirurgica·Amr Mohamed Nageeb El-ShehabyIgnatius Ngene Esene
Nov 5, 2008·Neurosurgery·Manish S SharmaL Dade Lunsford

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