Gamma Knife radiosurgery in the treatment of abducens nerve schwannomas: a retrospective study

Journal of Neurosurgery
Govindaraju Lakshmi PrasadBhawani Shankar Sharma

Abstract

OBJECTIVE Of the intracranial schwannomas, those arising from the vestibular nerves are the most common. Abducens nerve (AN) schwannomas are very rare, and there is limited literature on their optimal management. Therapeutic options include surgery and/or stereotactic radiosurgery. The aim of this study was to evaluate the role of Gamma Knife radiosurgery (GKRS) in these sixth cranial nerve (CN) schwannomas. METHODS The authors performed a retrospective analysis of patients who had undergone GKRS for intracranial tumors at their institute in the period from 2003 to 2010. Inclusion criteria were as follows: isolated AN paresis on presentation, a lesion along the course of the sixth CN, and imaging features characteristic of a schwannoma. Patients with other CN deficits and neurofibromatosis Type 2 were excluded. Symptomatic improvement was defined as the resolution of or an improvement in diplopia noted on a subjective basis or as an improvement in lateral eyeball excursion noted objectively on follow-up. A reduction in tumor volume by at least 20%, as noted by comparing the pre- and post-GKRS images, was deemed significant. RESULTS Six patients with a mean age of 37.1 years (range 17-55 years) underwent primary GKRS. There were...Continue Reading

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Citations

Oct 13, 2017·Acta neurochirurgica·Iulia Peciu-FlorianuMarc Levivier
Sep 30, 2017·Operative Neurosurgery·Giuseppe MarinielloFrancesco Maiuri
Dec 29, 2020·Surgical Neurology International·Zeyad M AlhussainFaisal Farrash

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