PMID: 7906923Mar 1, 1994Paper

Ganglioneuromas of the gastrointestinal tract. Relation to Von Recklinghausen disease and other multiple tumor syndromes

The American Journal of Surgical Pathology
K M Shekitka, L H Sobin


We studied 43 patients with ganglioneuromas of the gastrointestinal tract accessioned at the Armed Forces Institute of Pathology (AFIP) from 1940 to 1990 in order to determine their relation to von Recklinghausen's disease and other multiple tumor syndromes. They fell into three groups: polypoid ganglioneuroma (28 patients); ganglioneuromatous polyposis (7 patients); and diffuse ganglioneuromatosis (8 patients). Follow-up (1-24 years, average 8 years) for 16 of 28 patients with polypoid ganglioneuroma showed that none of these patients developed von Recklinghausen's disease or evidence or multiple tumor syndromes. Three of seven patients with ganglioneuromatous polyposis were alive and well but were reported to have multiple cutaneous lipomas and one reported a family history of multiple intestinal polyps. For seven of eight patients, diffuse ganglioneuromatosis was associated with other tumors, namely multiple endocrine neoplasia type IIb, multiple ganglioneuromas and neurofibromas limited to the gastrointestinal tract, von Recklinghausen's disease and neurogenic sarcoma. We conclude that the solitary polypoid ganglioneuroma of the gastrointestinal tract is not associated with the subsequent development of von Recklinghausen's...Continue Reading


Jul 1, 1997·Diseases of the Colon and Rectum·T K WuC Y Lee
Aug 15, 2013·Pediatric Surgery International·Florian Friedmacher, Prem Puri
Apr 7, 2005·Digestive Diseases and Sciences·Shazia RafiqMichael D Sitrin
Oct 2, 2012·The Indian Journal of Surgery·K PrakashPushpa Mahadevan
Feb 1, 1997·Journal of the American Academy of Dermatology·A R Lashgari, S F Friedlander
Feb 16, 1999·The American Journal of Surgical Pathology·P O'BrienA Gnidec
Nov 15, 2000·The American Journal of Surgical Pathology·Y M JengH C Hsu
Jan 1, 1997·Journal of Pediatric Gastroenterology and Nutrition·C L Cord-UdyP J Milla
Jan 1, 1997·Journal of Pediatric Gastroenterology and Nutrition·C D RudolphJ A Vanderhoof
Jul 20, 2002·Journal of Spinal Disorders & Techniques·Eric MarmorZiya L Gokaslan
Sep 15, 2005·The American Journal of Surgical Pathology·Marc R LewinElizabeth Montgomery
Jun 11, 2005·Journal of Gastroenterology and Hepatology·W I Al-DarajiW D Salman
Jan 1, 2011·BMJ Case Reports·Zubair AHmadAsim Qureshi
May 1, 2008·Diagnostic Pathology·Isabel Maria MendezAndres Sanchez
Sep 18, 2012·Journal of Medical Case Reports·Enrico FioriPietro Mingazzini
Mar 31, 2005·Journal of Neurosurgery. Spine·Ashok ModhaMark H Bilsky
Nov 26, 2008·World Journal of Gastroenterology : WJG·J-Elliot Carter, Javier-A Laurini
Oct 6, 2011·Archives of Pathology & Laboratory Medicine·Ahren C Rittershaus, Henry D Appelman
Nov 2, 2012·International Surgery·Hayato YamauchiHiroyuki Kuwano
Jun 6, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Ursula BasileGiorgio De Toma
Mar 31, 2005·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Angela D LevyLeslie H Sobin
Aug 29, 2012·Journal of Comparative Pathology·J K ParisS H Smith
Dec 30, 2015·The Korean Journal of Internal Medicine·Gu Hyum KangHoon Choi
Dec 17, 2014·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Emmanuel GizardLaurent Peyrin-Biroulet
Apr 8, 2015·Pathology International·Hiroshi MaruyamaChiho Ohbayashi
Jun 16, 2015·Case Reports in Gastrointestinal Medicine·George Abraham, Sateesh R Prakash
Jan 7, 2015·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Lysandra Voltaggio, Elizabeth A Montgomery
Sep 17, 2011·Clinics and Research in Hepatology and Gastroenterology·I AtitarN Amrani
Apr 22, 2004·AJR. American Journal of Roentgenology·Sridhar R CharagundlaJohn Rombeau
May 12, 2016·Hereditary Cancer in Clinical Practice·Steffen PistoriusHans K Schackert
Mar 24, 2009·Journal of Pediatric Surgery·Suk-Bae MoonSeong-Cheol Lee
Feb 24, 2007·Veterinary Pathology·B F PorterJ F Edwards
Jul 1, 2006·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Minzhi YinChung Wo Chow
Oct 7, 2014·Histopathology·Lysandra Voltaggio, Elizabeth Montgomery
Nov 27, 2016·Journal of Gastrointestinal Cancer·Mohamed AbdelfatahGlenn Harvin
Oct 1, 2003·American Journal of Medical Genetics. Part a·Mary P Bronner
Aug 21, 2015·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Tae Jun KimBong Hwa Lee

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adenomatous Polyposis Coli

Adenomatous polyposis coli is a protein encoded by the APC gene and acts as a tumor suppressor. Discover the latest research on adenomatous polyposis coli here.

Autoimmune Polyendocrine Syndromes

This feed focuses on a rare genetic condition called Autoimmune Polyendocrine Syndromes, which are characterized by autoantibodies against multiple endocrine organs. This can lead to Type I Diabetes.