PMID: 1203249Dec 17, 1975Paper

Gangliosides of the human gastrointestinal mucosa

Biochimica Et Biophysica Acta
A Keränen

Abstract

Gangliosides of the human alimentary mucosa were purified and analysed with thin-layer chromatography and gas chromatography. The content of ganglioside neuraminic acid was 0.16 mumol/g dry weight in the stomach, 0.07 mumol/g dry weight in the small intestine and 0.11 mumol/g dry weight in the large intestine. Mono- and disialosylhemosides were the major gangliosides, on a molar basis 68% of the total found in the stomach and 44% of the total in the small and large intestine. Considerable amounts of more complex gangliosides were found, especially in the small and large intestine, in which the molar content of tri- and tetraglycosylgangliosides containing galactosamine made up 38% of the total. Two glucosamine-containing gangliosides were also found, the probable structures of which were mono- and disialotetraglycosylceramide. The presence of the latter is reported for the first time.

References

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Citations

Nov 9, 2012·Journal of Virology·Miguel Angel MartínezPavel Isa
Oct 2, 2013·BioMed Research International·Krzysztof KurekMałgorzata Zendzian-Piotrowska
Mar 16, 2011·Journal of Digestive Diseases·Rui-Dong Duan
Jan 1, 1979·Archives of Oral Biology·U Lekholm, L Svennerholm
Oct 26, 1981·FEBS Letters·O NilssonL Svennerholm
Sep 26, 2017·Journal of Pediatric Gastroenterology and Nutrition·Irma Magaly Rivas-SernaMichael Thomas Clandinin
Sep 25, 2015·World Journal of Gastroenterology : WJG·John J MiklavcicM Tom Clandinin
Apr 22, 1976·Biochimica Et Biophysica Acta·A Keranen
Jul 1, 1976·Clinica Chimica Acta; International Journal of Clinical Chemistry·A KeränenK Puro
Sep 1, 1976·Chemistry and Physics of Lipids·A Keränen

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