Gardos pathway to sickle cell therapies?

Blood
C H Joiner

Abstract

In this issue of Blood, Ataga and colleagues report that treatment of sickle cell disease patients with senicapoc, a Gardos channel inhibitor, reduces the number of dehydrated cells, increases hemoglobin levels, and diminishes hemolysis.

Citations

Aug 30, 2008·Kidney International·Seth L Alper
Jul 17, 2015·American Journal of Hematology·Immacolata AndolfoAchille Iolascon
Oct 21, 2017·Blood·Patrick G Gallagher
Jan 18, 2020·Experimental Biology and Medicine·Madeleine LuVivien A Sheehan
Jun 25, 2020·American Journal of Physiology. Cell Physiology·Lennart KuckMichael J Simmonds

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