PMID: 9251230Aug 4, 1997Paper

Gas chromatographic examination of postmortem specimens after maprotiline intoxication

Forensic Science International : Synergy
T Keller, U Zollinger


Ingestion of an unknown quantity of Ludiomil (maprotiline)-costed tablets in a suicide is described. Although maprotiline is known for over 20 years now, relatively few cases of intoxications due to maprotiline overdose have been reported. The authors report a new and quick method to analyze and determine maprotiline and N-desmethylmaprotiline concentration in body fluids and postmortem specimens. The analytes and an internal standard (amitriptyline) were extracted from alkalinized samples into ethyl acetate before GC-NPD analysis. The proposed method resulted in a rapid procedure most useful in cases of deliberate poisoning with the tetracyclic antidepressant drug Ludiomil.


Oct 1, 1979·Biomedical Mass Spectrometry·D AlkalayM F Bartlett
Apr 1, 1990·Forensic Science International : Synergy·D J Pounder, G R Jones
Jan 1, 1989·Acta Psychiatrica Scandinavica. Supplementum·R D Farmer, R M Pinder
Jan 1, 1989·Acta Psychiatrica Scandinavica. Supplementum·E VuoriT Lahti
May 1, 1985·Journal of Clinical Pharmacology·E F Coccaro, L J Siever
Jun 1, 1984·Annals of Emergency Medicine·L NorthupR J Anderson
Jul 1, 1983·Journal of Analytical Toxicology·J S Salonen, M Scheinin
Jan 1, 1983·Therapeutic Drug Monitoring·F A Beierle, R W Hubbard
Jul 1, 1982·Journal of Analytical Toxicology·T A Rejent, R E Doyle
Nov 1, 1981·Acta Pharmacologica Et Toxicologica·J Kristinsson
Jul 21, 1995·Journal of Chromatography. B, Biomedical Applications·J IshidaM Yamaguchi
Jun 3, 1994·Journal of Chromatography. B, Biomedical Applications·H J KussD Y Zhao

❮ Previous
Next ❯


Oct 8, 2008·International Journal of Legal Medicine·Sarah M R WilleWilly E Lambert
Nov 4, 1998·Forensic Science International : Synergy·T KellerW Kisser
Mar 8, 2000·Forensic Science International : Synergy·T KellerE Tutsch-Bauer
Jan 17, 2016·Forensic Science International : Synergy·F BévalotL Fanton
Jun 3, 2004·Forensic Science International : Synergy·F MusshoffB Madea

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Epigenetics Insights from Twin Studies

Find the latest research on epigenetics and twin studies here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Related Papers

Forensic Science International : Synergy
T KellerR Dirnhofer
Journal of Analytical Toxicology
J CordonnierR De Keyser
© 2021 Meta ULC. All rights reserved