PMID: 3522115Jul 1, 1986

Gas exchange during mechanical ventilation and spontaneous breathing. Intermittent mandatory ventilation after open heart surgery

Chest
G WolffE Grädel

Abstract

Pulmonary gas exchange rates in eight patients after open heart surgery were studied during weaning from the ventilator. We investigated continuous positive pressure ventilation (CPPV), intermittent mandatory ventilation (IMV) and spontaneous breathing with continuous positive airway pressure (CPAP). During each mode of ventilation we measured: CO2 production (VCO2), O2 consumption (VO2), cardiac output (CO), PaO2, Qs/QT and functional residual capacity (FRC). In addition, we analyzed in each single breath: tidal volume (VT), series dead space volume (Vds), alveolar ventilation, alveolar efficiency for CO2 elimination (alv eff CO2) and end-tidal CO2 concentration (FCO2et). We compared the results of CPPV, IMV and CPAP and the mandatory breaths (MB) with the spontaneous breaths (SB) measured during IMV. CO was low during CPPV, when the patient still deeply sedated; it was increased in IMV and remained constant in the following CPAP period. VCO2 and VO2 did not differ significantly when switching from IMV to CPAP; therefore, work due to breathing seemed not to be reduced by the mandatory breath during IMV. Oxygenation (PaO2, Qs/QT) did not change significantly when switching from one mode to the other. FRC was constant when chang...Continue Reading

References

Nov 1, 1976·Critical Care Medicine·J B Downs, L A Mitchell
Dec 1, 1975·British Journal of Anaesthesia·G Hedenstierna, S Lundberg
Jan 1, 1985·International Journal of Clinical Monitoring and Computing·J X BrunnerG Cumming
Dec 1, 1972·Computers and Biomedical Research, an International Journal·M Paiva
Jan 1, 1984·International Journal of Clinical Monitoring and Computing·G Wolff, J X Brunner
Jan 1, 1980·International Anesthesiology Clinics·M E Douglas, J B Downs
Dec 1, 1980·Chest·J B Downs

Citations

Sep 26, 2012·Pulmonary Medicine·Nickolaos G KoulourisSofia-Antiopi Gennimata
Jul 4, 2001·American Journal of Respiratory and Critical Care Medicine·C PutensenN Mutz
Jan 20, 2006·Critical Care : the Official Journal of the Critical Care Forum·Lukas Brander, Arthur S Slutsky
Jan 1, 1997·Critical Care Medicine·C Putensen
Nov 14, 1997·Circulation·D N ThrushR A Smith
Feb 20, 2009·Anesthesia and Analgesia·Hermann HeinzeWolfgang Eichler
Sep 18, 2018·Anesthesia and Analgesia·Maximilian S SchaeferTanja Astrid Meyer-Treschan
Aug 26, 1998·Anesthesiology·E BratzkeR A Smith

Related Concepts

Breathalyzer Tests
Cardiac Surgery Procedures
Biphasic Intermittent Positive Airway Pressure
Positive End-Expiratory Pressure
Postoperative Procedures
Pulmonary Gas Exchange
Respiration
Respiratory Function Tests

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