Gas-flow assisted ion transfer for mass spectrometry

Journal of Mass Spectrometry : JMS
Sandilya GarimellaZheng Ouyang

Abstract

Methods and devices that use gas flows to collect ions and transfer them over long distances for mass spectrometric analysis have been developed. Gas flows derived from the ionization source itself or provided by means of additional pumping were used to generate a laminar flow inside cylindrical tube. Hydrodynamic simulations and experimental tests demonstrate that laminar flow can transfer ions over long distance. The typical angular discrimination effects encountered when sampling ions from ambient ionization sources are minimized, and the sampling of relatively large surface areas is demonstrated with desorption electrospray ionization (DESI). Ion transfer over 6 m has been achieved and its application to multiplexed chemical analysis is demonstrated on samples at locations remote from the mass spectrometer.

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Citations

Sep 18, 2013·Journal of the American Society for Mass Spectrometry·Sandilya GarimellaZheng Ouyang
Jan 11, 2013·Chemical Reviews·María Eugenia MongeFacundo M Fernández
Dec 5, 2015·Journal of Mass Spectrometry : JMS·Quan YuXiaohao Wang
Dec 3, 2014·Rapid Communications in Mass Spectrometry : RCM·Laine R ComptonAkos Vertes
Nov 14, 2012·Journal of Mass Spectrometry : JMS·Tsung-Chi ChenZheng Ouyang
Aug 6, 2015·Journal of the American Society for Mass Spectrometry·Sergey GimelsheinEugene Moskovets
Apr 8, 2016·Journal of the American Society for Mass Spectrometry·Sandilya V B GarimellaRichard D Smith
Mar 29, 2014·Mass Spectrometry Reviews·Gabor JarvasFrantisek Foret
Aug 4, 2015·Analytical Chemistry·Chien-Hsun ChenZheng Ouyang
Nov 19, 2014·Journal of the American Society for Mass Spectrometry·Chien-Hsun ChenZheng Ouyang
May 18, 2016·Scientific Reports·Benoit FatouIsabelle Fournier
Aug 20, 2016·Rapid Communications in Mass Spectrometry : RCM·Xiaoyu Zhou, Zheng Ouyang
Oct 27, 2016·Analytical Chemistry·William P McMahonKaveh Jorabchi
Feb 6, 2017·Journal of Mass Spectrometry : JMS·Y KostyukevichE Nikolaev
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Nov 29, 2017·Journal of the American Society for Mass Spectrometry·Tyler J YargerLane A Baker
Feb 15, 2018·Analytical Chemistry·Yury Kostyukevich, Eugene Nikolaev
Sep 2, 2020·Journal of the American Society for Mass Spectrometry·Jung Y LeeAndrei G Fedorov
Sep 2, 2020·Analytical Chemistry·Yuze LiZongxiu Nie
Oct 1, 2021·Electrophoresis·Husam KafeenahShu-Hui Chen

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