Gas-phase reactivity of aromatic sigma,sigma-biradicals toward dinucleoside phosphates

Organic Letters
Linan YangHilkka I Kenttämaa

Abstract

In order to improve the understanding of the interactions of aromatic sigma,sigma-biradicals with DNA, the reactivity of three isomeric sigma,sigma-biradicals toward four dinucleoside phosphates was studied in a mass spectrometer. The dinucleoside phosphates were evaporated into the mass spectrometer by using laser-induced acoustic desorption (LIAD). The results demonstrate that the structure of the sigma,sigma-biradical and the base sequence of the dinucleoside phosphate can have a major influence on these reactions.

References

Jul 18, 2001·Journal of the American Chemical Society·W T Johnson, C J Cramer
Feb 12, 2002·Journal of the American Society for Mass Spectrometry·Christopher J PetzoldHilkka I Kenttämaa
Feb 19, 2002·Chemical Reviews·Wendy Knapp Pogozelski, Thomas D. Tullius
Oct 10, 2002·Journal of the American Chemical Society·F Sedinam AmegayiborHilkka I Kenttämaa
Jan 8, 2003·Journal of the American Chemical Society·Jason M PriceChristopher J Cramer
Feb 6, 2003·Angewandte Chemie·Hans Henning WenkWolfram Sander
Feb 20, 2003·Journal of the American Chemical Society·Luis E Ramírez-ArizmendiHilkka I Kenttämaa
May 13, 2004·Journal of the American Chemical Society·Michael WinklerWolfram Sander
Jan 19, 2005·Accounts of Chemical Research·Peter R SchreinerMatthias Prall
Apr 21, 2005·Journal of the American Chemical Society·John J NashHilkka I Kenttämaa
Sep 15, 2005·Journal of the American Chemical Society·Ji-ang LiuHilkka Kenttämaa
Jul 29, 2006·Journal of the American Society for Mass Spectrometry·Courtney L ShermanSean M Kerwin
Aug 30, 2006·Journal of the American Society for Mass Spectrometry·Anthony AdeuyaHilkka I Kenttämaa

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Citations

Mar 21, 2013·Journal of the American Society for Mass Spectrometry·Linan YangHilkka I Kenttämaa
Aug 14, 2010·Journal of the American Society for Mass Spectrometry·Mingkun FuHilkka I Kenttämaa
Dec 17, 2009·Analytical Chemistry·Steven C HabichtHilkka I Kenttämaa
Aug 31, 2013·Chemical Reviews·Peggy E WilliamsHilkka I Kenttämaa
Dec 14, 2011·Journal of the American Chemical Society·Fanny WidjajaHilkka I Kenttämaa
May 30, 2012·European Journal of Mass Spectrometry·Alex M DowHilkka I Kenttämaa
May 1, 2017·Journal of the American Society for Mass Spectrometry·Fanny WidjajaHilkka I Kenttämaa
Oct 20, 2012·Analytical Chemistry·Sandra Osburn, Victor Ryzhov

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