Gastric bypass and cardiac autonomic activity: influence of gender and age.

Obesity Surgery
Marcos Borges MachadoAugusto Scalabrini-Neto

Abstract

Obesity is associated with increased sympathetic activity and higher mortality. Treatment of this condition is often frustrating. Roux-en-Y gastric bypass is the most effective technique nowadays for treatment of obesity. The aim of the present study is to assess the effects of this surgery on the cardiac autonomic activity, including the influence of gender and age, through heart rate variability (HRV) analysis. The study group consisted of 71 obese patients undergoing gastric bypass. Time domain measures of HRV, obtained from 24-h Holter recordings, were evaluated before and 6 months after surgery, and the results were compared. Percentage of interval differences of successive normal sinus beats greater than 50 ms (pNN50) and square root of the mean squared differences of successive normal sinus beat intervals (rMSSD) was used to estimate the short-term components of HRV, related to the parasympathetic activity. Standard deviation of intervals between all normal sinus beats (SDNN) was related to overall HRV. SDNN, pNN50, and rMSSD showed significant increase 6 months after surgery (p<0.001, p=0.001 and p=0.002, respectively). Men presented a greater increase of SDNN than women (p=0.006) during the follow-up. There was a diffe...Continue Reading

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Citations

Aug 14, 2012·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Silvia Leite FariaCynthia Buffington
Oct 8, 2009·Current Opinion in Lipidology·Nora E StraznickyElisabeth A Lambert
May 8, 2021·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Cicero Jonas R BenjamimVitor E Valenti
Aug 20, 2021·Clinical Obesity·Jawahar Al Nou'maniAhmed Al Qassabi

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