PMID: 11916345Mar 28, 2002Paper

Gastric cancer in sub-Saharan Africa

European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)
I SegalH Mitchell

Abstract

Gastric cancer has a variable but generally low prevalence in black populations of sub-Saharan Africa, despite a high prevalence of Helicobacter pylori (the 'African enigma'). Evidence from Soweto indicates that the host response to H. pylori may be protective against a virulent organism and that, in most people, H. pylori does not lead to more serious sequelae. This suggests that there may be host protective/inhibitory factors present, which prevent the progression of H. pylori-induced chronic active gastritis to cancer.

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Citations

Dec 8, 2004·Journal of Clinical Microbiology·Shannon L McNultyMark H Forsyth
Mar 2, 2011·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Meira EppleinWilliam J Blot
Dec 8, 2006·Infectious Agents and Cancer·Sam M MbulaiteyeMichie Hisada
Mar 20, 2012·BMC Research Notes·Kelias Phiri MsyambozaDamson Kathyola
Mar 11, 2009·Frontiers in Bioscience (Landmark Edition)·Sam M MbulaiteyeEmad M El-Omar
Jan 1, 2013·The Pan African Medical Journal·Firmin Ankouane AndouloKatleen Ngu Blackett
Nov 28, 2012·World Journal of Surgical Oncology·Joseph B MabulaHyasinta Jaka
Oct 13, 2010·Infectious Disease Clinics of North America·M Blanca PiazueloPelayo Correa
Apr 9, 2008·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·P Correa, M B Piazuelo
Sep 1, 2004·Alimentary Pharmacology & Therapeutics·R M Genta
Mar 26, 2005·Human Pathology·Massimo Rugge, Robert M Genta

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