Gastric microbiota in elderly patients fed via nasogastric tubes for prolonged periods

The Journal of Hospital Infection
R SegalA Leibovitz

Abstract

Aspiration of oropharyngeal contents is a constant threat for elderly patients fed via a nasogastric tube (NGT). Colonization of the oropharynx of these patients by pathological flora and the development of biofilms on the feeding tube has been documented recently. In addition, the presence of the NGT may interfere with the gastro-oesophageal sphincter, leading to gastro-oesophageal reflux. Thus, the passage of pathogenic bacteria in both directions is facilitated. The purpose of this study was to explore the microbiota of the gastric juice and the oropharynx in NGT-fed elderly patients. Samples of gastric juice were drawn after an overnight fast, and microbial cultures and direct pH measurement were performed. Concomitant cultures were obtained from the oropharynx. Overall, 107 gastric and oropharyngeal cultures were obtained from 52 subjects. Pathogenic flora (Gram-negative bacteria or Staphylococcus aureus) were isolated from 74% of stomach samples and from 69% of oropharynx samples. Proteus spp. (26%) and Escherichia coli (22%) were the most common isolates in the gastric juice, and Proteus spp. (24%) and Pseudomonas spp. (21%) were the most common isolates in the oropharynx. Similarity in the composition of the oropharynx ...Continue Reading

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Citations

Nov 22, 2011·Revue des maladies respiratoires·F PuisieuxUNKNOWN Intergroupe PneumoGériatrie SPLF–SFGG placé sous l’égide de la Société de pneumologie de langue française (SPLF) et de la So
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Dec 14, 2011·Pediatric Pulmonology·Kara PalmRachel Rosen
Nov 20, 2013·Journal of Digestive Diseases·Wen Ming WuLi Hua Peng
Apr 27, 2013·Pathogens and Disease·Erik C von RosenvingeMark E Shirtliff
Jun 15, 2018·Clinical Microbiology Reviews·Amy L HamiltonMark Morrison

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