Gastric relaxation in response to a soup meal in healthy subjects. A study using a barostat in the proximal stomach

Scandinavian Journal of Gastroenterology
K A UndelandA Berstad

Abstract

Meal-induced relaxation of the proximal stomach can be investigated by means of a barostat. Using a standard liquid meat soup that elicits symptoms and a wide antrum in patients with functional dyspepsia, we aimed at finding the best meal size and fat load for studying gastric relaxation. In the first trial 200 ml and 500 ml meat soup (1 g fat/200 ml) was given to six healthy individuals. In the second trial a constant volume of soup (200 ml) containing graded amounts of fat (1, 10, and 20 g/200 ml) was given to seven healthy individuals. Gastric relaxation was investigated for 1 h after consumption of the soup. A sagittal cross-sectional antral was assessed ultrasonographically every 10 min, and abdominal discomfort was scored. Overall, a positive response (volume increase of 30 ml or more within 5 min after consumption of the meal) was found in 26 of 30 (87%) investigations. Individual maximal responses ranged from 38 to 482 ml (mean, 180 ml +/- 128). Area under the time-volume curve (AUC) was similar after 200 and 500 ml soup (mean, 100 ml/30 min and 107 ml/30 min, respectively). AUC increased with increasing fat content, with a significant difference between the low-fat and high-fat meal (p < 0.05). The barostat bag induced...Continue Reading

References

May 1, 1992·Scandinavian Journal of Gastroenterology·T Hausken, A Berstad
Oct 1, 1991·Gastroenterology·F MearinJ R Malagelada
May 1, 1990·Gastroenterology·F Azpiroz, J R Malagelada
Sep 1, 1989·Journal of Gastroenterology and Hepatology·R HeddleL A Houghton
Mar 1, 1987·The Journal of Physiology·F Azpiroz, J R Malagelada
Nov 1, 1986·The American Journal of Physiology·M S ParmacekA M Samarel
Jun 1, 1987·The American Journal of Physiology·S Sanchez-Armass, M P Blaustein
Sep 1, 1994·Scandinavian Journal of Gastroenterology·K HveemA Berstad
Dec 1, 1993·Journal of Clinical Gastroenterology·T AburanoK Kobayashi

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Citations

Apr 1, 1996·Digestive Diseases and Sciences·O H GiljaA Berstad
Sep 7, 2000·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·P PortincasaD Festi
Jun 25, 2004·Journal of Smooth Muscle Research = Nihon Heikatsukin Gakkai Kikanshi·Masafumi Kikkawa
Oct 1, 2003·British Journal of Pharmacology·P JanssenR A Lefebvre
Oct 30, 2004·Scandinavian Journal of Gastroenterology·I E HjellandT Hausken
May 5, 2001·Scandinavian Journal of Gastroenterology·P J van der SchaarA A Masclee
Dec 23, 2003·The American Journal of Gastroenterology·Isabelle Le Blanc-LouvryPhilippe Ducrotté
Dec 3, 1999·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·B MearadjiA A Masclee
May 16, 2006·Alimentary Pharmacology & Therapeutics·B D J van den Elzen, G E E Boeckxstaens
Jun 7, 2005·American Journal of Veterinary Research·Mireia Lorenzo-FiguerasAlfred M Merritt
Mar 1, 1997·Scandinavian Journal of Gastroenterology·A BerstadT T Haug
Oct 1, 1998·Scandinavian Journal of Gastroenterology·T HauskenA Berstad
Sep 28, 1999·Scandinavian Journal of Gastroenterology. Supplement·P J van der SchaarA A Masclee
Jun 5, 1998·The American Journal of Physiology·J W StraathofA A Masclee

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