Gastric xanthelasma associated with hyperplastic polyp and mucosal erosions: report of an unusual case and literature review

Oxford Medical Case Reports
Malak AlzahraniAmmar C Al-Rikabi

Abstract

Gastric xanthelasma is a rare benign tumor-like lesion which is usually observed as an incidental finding due to its asymptomatic presentation. Grossly, it is a well-demarcated yellow-white plaque which is microscopically formed by clusters of foamy macrophages in the lamina propria. The pathogenesis and clinical significance are not clear. Gastric hyperplastic polyps are rarely associated with xanthelasma. Mucosal erosions also appear to have an association with the combined lesions of hyperplastic polyp and xanthelasma. Here, we report a rare case of simultaneous occurrence of gastric xanthoma with hyperplastic polyp and mucosal erosions. The lesions are observed in a 78 years old male who presented with a history of chronic anemia. The histological features together with a literature review of other similar reported cases are described and compared.

References

Sep 1, 1991·Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics·M NaitoF Kuzuya
Jun 12, 1999·Scandinavian Journal of Gastroenterology·H IsomotoS Kohno
Oct 17, 2003·World Journal of Gastroenterology : WJG·Rasim GencosmanogluNurdan Tozun
Apr 6, 2004·Journal of Gastroenterology·Rasim GencosmanogluNurdan Tozun
Nov 28, 2008·Digestive Diseases and Sciences·Richa Jain, Runjan Chetty
Oct 30, 2013·BMJ Case Reports·Mona DhakalAmlan Gupta
Jan 1, 2014·Journal of Gastroenterology and Hepatology·Akira SekikawaYukio Osaki
Jun 3, 2016·Digestive Diseases and Sciences·Aydın Şeref KöksalErkan Parlak

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Citations

Jan 29, 2020·Pediatric Gastroenterology, Hepatology & Nutrition·Joseph D RussellMichael J Wilsey

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