PMID: 7034160Jan 1, 1981Paper

Gastrin secretion before and after gastric bypass surgery for morbid obesity

Scandinavian Journal of Gastroenterology
E SchrumpfO Fausa

Abstract

Fasting, meal-stimulated, and insulin-hypoglycemia-stimulated serum gastrin levels were measured before and 3 and 12 months after gastric bypass surgery in nine obese patients. The basal gastrin concentration was unaffected by the operation. After a meal both serum gastrin and blood glucose levels were significantly increased before the operation (p less than 0.002), whereas there was no significant gastrin release in response to food 3 and 12 months after the operation. Insulin hypoglycemia did not elicit any gastrin response either before or after gastric bypass surgery, even though considerable hypoglycemia was obtained. It is concluded that this lack of gastrin release after food and insulin hypoglycemia postoperatively may in part explain the rare development of peptic ulcer in patients after extensive gastric exclusion.

References

Feb 1, 1976·American Journal of Surgery·E E MasonK J Printen
Jan 1, 1972·Scandinavian Journal of Gastroenterology·F Stadil, J F Rehfeld
Jan 1, 1972·Scandinavian Journal of Gastroenterology·E Schrumpf, T Sand
Aug 1, 1969·American Journal of Surgery·J H Payne, L T DeWind
Sep 1, 1969·Annals of Surgery·E E Mason, C Ito
Aug 1, 1963·American Journal of Surgery·J H PAYNER R COMMONS

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Citations

Feb 1, 1989·Regulatory Peptides·R A PedersonJ C Brown
Aug 1, 1997·The Australian and New Zealand Journal of Surgery·R V LordM J Coleman
Apr 29, 2006·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·Björn StenstromDuan Chen
Dec 24, 2013·Diabetes & Metabolism·I QuerciaB Laferrère
Oct 4, 2006·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Hongchan LeeBlandine Laferrère
Mar 19, 2013·International Journal of Surgery Case Reports·Rhiannon ChapmanMarco Adamo
Aug 16, 2005·American Journal of Physiology. Gastrointestinal and Liver Physiology·Tom C MartinsenHelge L Waldum
Nov 7, 2019·Updates in Surgery·María A CasasMarco G Patti
Jun 3, 2021·Children·Valeria CalcaterraFatima Cody Stanford

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