PMID: 6108304Jan 1, 1980Paper

Gastrin/CCK-like immunoreactivity in the nervous system of coelenterates

Histochemistry
C J GrimmelikhuijzenJ F Rehfeld

Abstract

Using immunocytochemistry, gastrin/CCK-like immunoreactivity is found in sensory nerve cells in the ectoderm of the mouth region of hydra and in nerve cells in the endoderm of all body regions of the sea anemone tealia. These results are corroborated by radioimmunoassay: One hydra contains at least 5 fmole and one tealia at least 2 nmole gastrin/CCK-like immunoreactivity. Reactivities towards gastrin and CCK antisera with different specificities suggest that the coelenterate gastrin/CCK-like peptide contains the C-terminal amino-acid sequence common to mammalian gastrin and CCK. In addition the radioimmunochemical data indicate that the coelenterate peptide also contains an amino-acid sequence that resembles the sequence 20-30 of porcine CCK-33, but that no other sequences of gastrin are present. Thus, it is probably more CCK-like than gastrin-like.

References

Jun 1, 1978·Journal of Neurocytology·J A Westfall, J C Kinnamon
Jun 15, 1979·Experientia·C H Taban, M Cathieni
Jan 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·E Straus, R S Yalow
Jan 1, 1979·The Journal of Physiology·J AlumetsF Sundler
Aug 1, 1977·General and Comparative Endocrinology·K J KramerC N Childs
Nov 14, 1975·Science·E StrausH Gainer
Oct 1, 1972·Scandinavian Journal of Clinical and Laboratory Investigation·J F RehfeldB Rubin
Apr 1, 1968·Archives of Biochemistry and Biophysics·A AnastasiR Endean
Apr 1, 1980·General and Comparative Endocrinology·T CreaghD Powell

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Citations

Jan 1, 1981·Histochemistry·C J GrimmelikhuijzenN Yanaihara
Jan 1, 1982·Histochemistry·C J GrimmelikhuijzenL P Schot
Jan 1, 1981·Histochemistry·C J GrimmelikhuijzenF Sundler
Jan 1, 1981·Histochemistry·C J GrimmelikhuijzenF Sundler
Jan 1, 1988·Comparative Biochemistry and Physiology. A, Comparative Physiology·R E HonkanenJ S Patton
Aug 1, 1983·Neuroscience·C J Grimmelikhuijzen
Jan 1, 1983·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·J Van MarleA Lind
Jan 1, 1984·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·G VenturiniV Margotta
Jan 1, 1988·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·G B Stefano
Jan 1, 1988·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·P F Basch, B C Gupta
Jun 1, 1983·General and Comparative Endocrinology·B A Larson, S R Vigna
Nov 15, 2006·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·G Kass-Simon, Paola Pierobon
Sep 1, 2005·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·Markus SchweigerWerner M Amselgruber
Jul 8, 1996·The Journal of Comparative Neurology·P SithigorngulA O Stretton
Sep 9, 1996·The Journal of Comparative Neurology·M SakaguchiY Kobayakawa
Dec 1, 1986·The American Journal of Physiology·B S SchneiderJ Friedman
Feb 20, 2015·The Journal of Experimental Biology·Stefan Gründer, Marc Assmann

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