PMID: 9446923Feb 3, 1998Paper

Gastro-oesophageal reflux disease in institutionalised intellectually disabled individuals

The Netherlands Journal of Medicine
C J BöhmerS G Meuwissen

Abstract

The prevalence of reflux oesophagitis (RO) in the normally intellectual population is about 2%, while this condition in the intellectually disabled has an estimated prevalence of 10%. We investigated the presence of RO among 1687 intellectually disabled, with an IQ < 50, from 5 different institutes in the Netherlands. All were scored for possible associated factors and reflux symptoms, and compared with the overall population (n = 1580) from the same institutes (controls). Also, the effect of treatment on symptoms was evaluated after at least one year of therapy. Gastro-oesophageal reflux disease (GORD) was suspected clinically in 169 patients based on the following symptoms: vomiting, haematemesis, anaemia, rumination or behaviour problems. At endoscopy RO was diagnosed in 107 of 1687 patients (6.4%): 17 (15.9%) grade I, 34 (31.8%) gr. II, 42 (39.3%) gr. III and 14 (13.1%) gr. IV RO (Savary-Miller classification). Cerebral palsy, constipation, anticonvulsant drugs, an IQ < 35, underweight and gastrostomy feeding appeared to be possible associated factors, while as reflux symptoms persistent vomiting, haematemesis, iron deficiency anaemia, rumination, and behaviour problems were found. Concerning therapy, surgery was found to b...Continue Reading

Citations

Jun 13, 2008·BMC Gastroenterology·Anke J E de VeerAnneke L Francke
Jul 23, 2008·Developmental Disabilities Research Reviews·Peter B Sullivan
Sep 12, 2006·Journal of Intellectual Disability Research : JIDR·G Galli-CarminatiN Deriaz
Jul 19, 2011·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Irène BenigniDavid Seguy
Dec 22, 2011·Research in Developmental Disabilities·Masoumeh DouraghiBahram Nikmanesh
Aug 19, 2000·The American Journal of Gastroenterology·C J BöhmerS G Meuwissen
Mar 11, 2010·International Journal of Rehabilitation Research. Internationale Zeitschrift Für Rehabilitationsforschung. Revue Internationale De Recherches De Réadaptation·Gulten ErkinEylem Gulsen Kirbiyik
Jan 8, 2008·Southern Medical Journal·Kamran KhalidNasser Faleh Al-Dossary
Mar 4, 2011·Journal of Intellectual Disability Research : JIDR·C F de WinterH M Evenhuis

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Related Papers

Advances in Dental Research
H Slavkin
Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus
S J WalkerN Birbeck
© 2021 Meta ULC. All rights reserved