PMID: 7023396Sep 1, 1981Paper

Gastroduodenal complications in kidney transplant recipients

Annals of Surgery
F P StuartB L Ketel

Abstract

Oral antacids taken every two hours while awake provided the only prophylaxis against gastroduodenal ulceration for 167 kidney transplant recipients between 1968 and July 1978. Either perforation or major hemorrhage occurred in eight patients within 30 days after transplantation. Between July 1978 and January 1981, bleeding occurred within 30 days in two of 147 recipients who were treated with both antacids and cimetidine. Of the 147 patients, eleven with a history of ulcers had undergone pretransplant vagotomy; neither perforation nor hemorrhage occurred in any of the eleven patients. Despite reports that cimetidine enhances certain types of immune responses, we observed slightly greater graft survival in the group treated with cimetidine.

References

Apr 1, 1979·Archives of Surgery·L F MartinM H Max
Jun 10, 1978·Lancet·B Charpentier, D Fries
May 19, 1979·Lancet·J L Hussey, F O Belzer
Jun 30, 1979·Lancet·M D SmithJ R Salaman
Jun 25, 1977·British Medical Journal·G D ChisholmJ H Baron
Nov 1, 1979·Transplantation·E H GoldbergR C Williams
Feb 1, 1975·American Journal of Surgery·J S AldreteA G Diethelm
Jun 16, 1973·Lancet·A M ShepherdK G Wormsley
Aug 1, 1974·Archives of Surgery·P K SpanosJ S Najarian
Jan 1, 1980·Annals of Surgery·F P StuartJ A Schulak
Mar 1, 1981·American Journal of Surgery·R I WesdorpJ E Fischer
Feb 21, 1980·The New England Journal of Medicine·R Menguy
Feb 1, 1980·Annals of Internal Medicine·J L JorizzoA J Olansky

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Citations

Jan 1, 1993·Transplant International : Official Journal of the European Society for Organ Transplantation·G BenoitD Fries
Feb 1, 1993·Digestive Diseases and Sciences·J Y Kang
Aug 1, 1984·The British Journal of Surgery·G A KhouryO N Fernando

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