PMID: 3758011Jul 1, 1986Paper

Gastroduodenal ulceration in foals

Equine Veterinary Journal
J L Becht, T D Byars

Abstract

Gastroduodenal ulceration is becoming recognised as an important disease in foals during the first few months of life. Aetiopathogenesis is presumed to be similar to peptic disease in humans associated with back diffusion of hydrogen ions into the mucosa. Many factors have been incriminated as predisposing foals to ulceration but few have been proven. To date, use of non-steroidal anti-inflammatory agents has been the only documented cause of gastroduodenal ulceration in foals. The clustering of affected foals on certain farms suggests an infectious aetiology but attempts to identify a causative organism have been unsuccessful. Four clinical syndromes defined for foals with gastroduodenal ulceration include: silent ulcers, which occur most often in the non-glandular stomach along the margo plicatus and are identified as incidental findings at necropsy; active ulcers which are often manifested by abdominal pain, excessive salivation and bruxism; perforating ulcers which usually result in a severe, diffuse peritonitis; and pyloric or duodenal obstruction from a healing ulcer. General approaches to therapy of a foal with active ulceration consist of reduction of gastric acidity and enhancement of mucosal protection. Antacids and t...Continue Reading

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Citations

Mar 1, 1992·Australian Veterinary Journal·J A Laing, D R Hutchins
Feb 25, 2006·Journal of Veterinary Internal Medicine·Jennifer TaintorJohn Schumacher
Jan 1, 1990·Equine Veterinary Journal·M C Roberts
Jan 1, 1990·Equine Veterinary Journal·M J MurrayS J Stoneham
Jan 1, 1990·Equine Veterinary Journal·G B SmythC R Clark
Jan 1, 1992·Equine Veterinary Journal·R L YoungH J Olander
Sep 1, 1992·Journal of Veterinary Internal Medicine·C G MacAllisterA Mauromoustakos
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Jul 30, 2005·The Veterinary Clinics of North America. Equine Practice·Clare A Ryan, L Chris Sanchez
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