Gastroenteropancreatic neuroendocrine neoplasms-Heterogeneity, management and perspectives of treatment and research

Der Internist
K LuleyS M Schmid

Abstract

The term neuroendocrine neoplasms (NEN) encompasses a molecularly and biologically very heterogeneous group of tumors, which have in common their origin in neuroendocrine cells. The also very heterogeneous subgroup of gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN) is the best classified and investigated group. This article provides a systematic review of the current classification, diagnostics and treatment options of GEP-NEN. In order to achieve a better overview, it was consciously decided not to use an approach based on the primary localization. Instead, a thematic organization according to classification, clinical phenotype, diagnostics and treatment was chosen.

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Apr 3, 2021·World Journal of Gastrointestinal Surgery·Cornelius J FernandezJoseph M Pappachan

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