PMID: 9113312Dec 1, 1996Paper

Gastrointestinal endocrine tumours. Pathology

Baillière's Clinical Gastroenterology
A E Bishop, J M Polak


Neuroendocrine tumours can form in any part of the gastrointestinal tract. The most common types are the ECL cell tumours of the oxyntic mucosa of the stomach, G cell tumours of the duodenum, argentaffin, EC cell tumours of the small intestine and L cell tumours of the large bowel. The only well-defined clinical syndromes associated with hormone hypersecretion are ZES, resulting from duodenal gastrinomas, and carcinoid syndrome, caused by malignant argentaffin tumours. Genetic predisposition has been demonstrated for some tumour types, e.g. duodenal gastrinoma in MEN 1 and duodenal somatostatin cell tumours in MEN 2. Other factors predisposing to the genesis of these lesions include circulating hormone levels and the maintenance of chronic inflammatory states. As with most neuroendocrine tumours, malignant potential is difficult to assess on the basis of histology alone and prognostic evaluation depends more on size and evidence of local invasion and/or distant metastases.


Mar 1, 1978·The American Journal of Surgical Pathology·V E Gould, G Chejfec
Mar 15, 1990·The New England Journal of Medicine·M Pipeleers-MarichalP U Heitz
Dec 1, 1990·Histopathology·D C Brown, K C Gatter
May 1, 1986·The American Journal of Surgical Pathology·Y DayalH J Wolfe
Aug 1, 1987·American Journal of Clinical Pathology·C BordiA Peracchia
Aug 1, 1988·Alimentary Pharmacology & Therapeutics·J M Polak, S R Bloom
Jan 1, 1986·Digestion·E SolciaL Villani
Aug 1, 1973·Archives of Surgery·J W HofmannS D Wilson
Jul 1, 1971·Cancer·M J Orloff
Oct 1, 1983·Annals of Surgery·C W DeveneyL W Way
Oct 1, 1983·The American Journal of Surgical Pathology·Y DayalH J Wolfe
Feb 1, 1984·Journal of Clinical Pathology·D F GriffithsG T Williams
Apr 1, 1981·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·S M HsuH Fanger
Jan 1, 1983·Virchows Archiv. A, Pathological Anatomy and Histopathology·L Auböck, H Höfler
Jul 1, 1980·Ultrastructural Pathology·C V ReyesV E Gould
Jan 18, 1958·Lancet·M SANDLER, P J SNOW
Feb 2, 1963·Lancet·E D WILLIAMS, M SANDLER

❮ Previous
Next ❯


Mar 18, 1999·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·F YuR T Jensen
Jun 8, 2004·Endocrine Reviews·Gregory A KaltsasAshley B Grossman
Sep 18, 2007·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·O BigeU Saygili
Nov 14, 2007·European Journal of Gastroenterology & Hepatology·Dimitrios PapadogiasGregory Kaltsas

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.