Gastrointestinal involvement in neurologic disorders: Stiff-man and Charcot-Marie-Tooth syndromes

The American Journal of the Medical Sciences
I Soykan, R W McCallum

Abstract

Many neurologic conditions can affect the striated muscle of the gastrointestinal tract, resulting in dysphagia. In this article, two patients with rare neurologic disorders are reported (Stiff-man syndrome and Charcot-Marie-Tooth syndrome). Both patients had pharyngeal dysphagia. In addition, there was evidence of smooth muscle involvement in other areas of the gastrointestinal tract, specifically abnormal esophageal motility and delayed gastric emptying. In the English literature, there are only two reports of Stiff-man syndrome and dysphagia, and there are no reports of Charcot-Marie-Tooth syndrome. These represent the first accounts of smooth muscle dysfunction in those uncommon neurologic disorders.

References

Apr 21, 1988·The New England Journal of Medicine·R B Layzer
Jan 1, 1970·The American Journal of Digestive Diseases·M J SulwayE Davis
Dec 1, 1994·The Journal of Neuroscience Nursing : Journal of the American Association of Neuroscience Nurses·P T Spada, J B Spada
Jun 13, 1994·Archives of Internal Medicine·D Tarsy, E K Miyawaki

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Citations

Jul 14, 1999·Arthritis and Rheumatism·S M Helfgott
Jul 20, 2011·Nature Reviews. Gastroenterology & Hepatology·William L Hasler
Aug 2, 2020·Journal of Veterinary Internal Medicine·Alba Farré MarinéAlejandro Luján Feliu-Pascual
May 26, 2021·Journal of Gastroenterology and Hepatology·Shinwa TanakaHaruhiro Inoue

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