PMID: 11321347Apr 26, 2001Paper

Gastrointestinal stromal tumor of the stomach: report of a case

Surgery Today
H ShiraiH Ito

Abstract

We report herein the case of a 70-year-old woman found to have a gastrointestinal stromal tumor (GIST) of the stomach. Preoperative X-ray and endoscopic examination revealed a hemispheric submucosal tumor with central depression in the anterior wall of the gastric fornix. The tumor, which was 3 cm in diameter, was resected by a laparoscopy-assisted procedure. Histologic examination revealed that it was composed of spindle-shaped cells with elongated nuclei, and few mitoses. Most of the tumor cells showed immunoreactivity for vimentin and CD34, but not for alpha-smooth muscle actin, desmin, or S-100 protein. The PCNA index was 40.5%. Thus, the GIST did not show differentiation toward smooth muscle or neural cells. A gastrectomy was not performed because the small size of the tumor, and the paucity of the mitoses indicated that it was benign. Nevertheless, careful and long-term follow-up is needed to monitor for signs of possible local recurrence or distant metastases.

Citations

Aug 9, 2005·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Hiroshi YanoShigeru Okamoto
Apr 24, 2007·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Roberta GelminiPier Franco Conte
May 5, 2004·Annals of Surgical Oncology·Burton L Eisenberg, Ian Judson

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