Gastrointestinal stromal tumors of the stomach: CT findings and prediction of malignancy

AJR. American Journal of Roentgenology
Hyo-Cheol KimByung Ihn Choi

Abstract

The purpose of this study was to identify predictors of malignancy on CT for the evaluation of gastrointestinal stromal tumors of the stomach. The medical records at our institution of 81 patients with a histologic diagnosis of gastrointestinal stromal tumor of the stomach were reviewed. Two radiologists retrospectively reviewed the CT findings by consensus with respect to lesion size, contour, tumor growth pattern, enhancing pattern, degree of enhancement, mesenteric fat infiltration, ulceration, calcification, lymphadenopathy, direct invasion to adjacent organ, and distant metastasis. Categoric variables were compared using the chi-square or Fisher's exact test. Multiple stepwise logistic regression analysis by means of forward selection was performed to determine significant predictors of high mitotic rate. Univariate analysis and multivariate analysis were also performed in a subgroup of 36 tumors with maximal diameter of 5 cm or smaller. Size, presence of an ulcer, mesenteric fat infiltration, direct organ invasion, and metastasis were more frequently observed during univariate analysis in tumors with a high mitotic rate (p < 0.05). With stepwise logistic regression analysis, the size (odds ratio, 2.57; 95% CI; 1.42-4.67) ...Continue Reading

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