Gastrointestinal transit of undigestible solids measured by metal detector EAS II

European Journal of Clinical Investigation
K EweW Dederer

Abstract

A new method was developed to measure gastrointestinal transit: a metal particle is followed on its way through the gastrointestinal tract by means of a portable metal detector. Deviation of measured localization of the metal particle from the exact site was 0.5-1.0 cm depending on its size and distance from the search probe. A metal sphere of 6 mm diameter can be located accurately in the body at a distance of 2-12 cm from the abdominal surface. Emptying of a metal particle from the stomach, its arrival at the caecal area and its passage through the colon into the rectum can be registered and hence, gastric residence time, small intestinal transit and transit through different parts of the colon were determined. Gastric residence time at the interdigestive phase was (mean +/- SD) 67 +/- 52 min in 20 persons with a range of 9-185 min. When gastric emptying was recorded by pH sensitive radiotelemetering capsule in 10 persons, correlation of both methods was r = 0.99. Small intestinal transit averaged 110 +/- 56 min in six healthy volunteers when breakfast was eaten after the marker had left the stomach. It was delayed to 218 +/- 34 min (P less than 0.01) when fasting was continued. Large intestinal transit of the metal marker wa...Continue Reading

References

Jun 1, 1988·Gastroenterology·J H MeyerG L Amidon
Nov 1, 1987·Gastroenterology·S S RaoC D Holdsworth
Jan 1, 1986·Gastroenterology·N W ReadJ J Bannister
Dec 1, 1983·Australian and New Zealand Journal of Medicine·P KerlinS F Phillips
Apr 1, 1982·Gut·S HoltR C Heading

❮ Previous
Next ❯

Citations

Jan 1, 1993·European Journal of Drug Metabolism and Pharmacokinetics·B Oosterhuis, J H Jonkman
Jul 22, 2005·International Journal of Clinical Practice·G P Conners
Jun 1, 1993·The British Journal of Oral & Maxillofacial Surgery·U J MooreM J Gross
Sep 5, 2002·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Roman SchwarzBasil Künnecke
Aug 1, 1994·Biopharmaceutics & Drug Disposition·H TakahashiH Shimamura
Apr 12, 2006·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Vadim B Warshavsky, Xueyu Song
Jan 27, 2005·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·E StathopoulosP Kucera
Feb 1, 1995·Alimentary Pharmacology & Therapeutics·K EweM Klump
Jan 1, 1992·European Journal of Clinical Pharmacology·I Walter-Sack

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.