Gastroparesis in a Patient with Gastric AL Amyloidosis

Case Reports in Gastroenterology
Matthew HoscheitMichael Cline

Abstract

Systemic amyloidosis is a group of complex disorders characterized by the extracellular deposition of nonbranching fibrils in various tissues, ultimately leading to a variety of clinical presentations including isolated or multiorgan dysfunction. Amyloid involvement of the gastrointestinal tract is common depending on the subtype of this disease; light chain primary amyloidosis (AL) and secondary amyloidosis (AA) affect the gastrointestinal tract in unique ways due to differing pathophysiology. A case is reported of gastroparesis associated with AL amyloidosis diagnosed by esophagogastroduodenoscopy and study of gastric emptying, then subsequently confirmed by Congo red staining performed on endoscopic biopsies.

References

Aug 1, 1993·Mayo Clinic Proceedings·D M MenkeW A Oldenburg
Oct 26, 2001·Postgraduate Medical Journal·M F Khan, R H Falk
Aug 21, 2007·Clinical Journal of the American Society of Nephrology : CJASN·Vaishali Sanchorawala
Mar 28, 2008·Alimentary Pharmacology & Therapeutics·S PetreN Gilani
Jun 27, 2012·Haematologica·Andrew J CowanVaishali Sanchorawala
Feb 26, 2016·Virchows Archiv : an International Journal of Pathology·Sophie FreudenthalerChristoph Röcken

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Citations

Feb 2, 2021·Hematology/oncology Clinics of North America·Michael Rosenzweig, Efstathios Kastritis
Apr 28, 2020·Acta Haematologica·Iuliana Vaxman, Morie Gertz

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Methods Mentioned

BETA
biopsies
electrophoresis
biopsy

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