Gate effects on DNA translocation through silicon dioxide nanopore

The Review of Scientific Instruments
Pei-chun YenY C Chou

Abstract

The effects of gate voltage on the translocation of DNA molecules through a nanopore are studied. A twenty-fold increase in the translocation time is observed with a positive gate voltage applied, without changing too much of the ionic current. The amplitude of the current blockage by the DNA molecules was reduced by roughly the same factor. At the same time, the number of the blocking events decreases significantly. The applied gate voltage also modulates the scatter plot of the amplitude of the current blockage against the dwell time. The observations are consistent with the recent theoretical results.

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Citations

May 22, 2013·Nanoscale Research Letters·Yin ZhangYunfei Chen
Oct 7, 2015·Physical Chemistry Chemical Physics : PCCP·Yong Youn, Seungwu Han
May 2, 2015·Electrophoresis·Matthew WaughVincent Tabard-Cossa
Jul 16, 2017·Physical Review. E·Thomas Töws, Peter Reimann
Feb 2, 2013·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Ining A JouMaria E Gracheva
Jul 16, 2013·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Sebastian GetfertPeter Reimann

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Methods Mentioned

BETA
optical tweezer
chip

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