Gate effects on DNA translocation through silicon dioxide nanopore

The Review of Scientific Instruments
Pei-chun YenY C Chou


The effects of gate voltage on the translocation of DNA molecules through a nanopore are studied. A twenty-fold increase in the translocation time is observed with a positive gate voltage applied, without changing too much of the ionic current. The amplitude of the current blockage by the DNA molecules was reduced by roughly the same factor. At the same time, the number of the blocking events decreases significantly. The applied gate voltage also modulates the scatter plot of the amplitude of the current blockage against the dwell time. The observations are consistent with the recent theoretical results.


Nov 26, 1996·Proceedings of the National Academy of Sciences of the United States of America·J J KasianowiczD W Deamer
Feb 3, 2000·Proceedings of the National Academy of Sciences of the United States of America·A MellerD Branton
Mar 31, 2000·Trends in Biotechnology·D W Deamer, M Akeson
Oct 16, 2002·Accounts of Chemical Research·David W Deamer, Daniel Branton
Aug 28, 2003·Nature Materials·Jiali LiJ A Golovchenko
Mar 5, 2004·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Yacov Kantor, Mehran Kardar
Aug 25, 2004·Physical Review Letters·Derek SteinCees Dekker
May 12, 2005·Nano Letters·Rohit KarnikArun Majumdar
Aug 11, 2005·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·A J StormC Dekker
Sep 15, 2005·Nano Letters·Daniel FologeaJiali Li
Jun 27, 2006·Biomedical Microdevices·Hung ChangRashid Bashir
Aug 21, 2007·Nano Letters·Eliane H TrepagnierJan Liphardt
Apr 27, 2011·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Zhijun Jiang, Derek Stein
Oct 24, 2007·Nanotechnology·Xiongce ZhaoJames W Lee
Nov 1, 2004·Nano Letters·Peng ChenDaniel Branton

❮ Previous
Next ❯


May 22, 2013·Nanoscale Research Letters·Yin ZhangYunfei Chen
Oct 7, 2015·Physical Chemistry Chemical Physics : PCCP·Yong Youn, Seungwu Han
May 2, 2015·Electrophoresis·Matthew WaughVincent Tabard-Cossa
Jul 16, 2017·Physical Review. E·Thomas Töws, Peter Reimann
Feb 2, 2013·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Ining A JouMaria E Gracheva
Jul 16, 2013·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Sebastian GetfertPeter Reimann

❮ Previous
Next ❯

Methods Mentioned

optical tweezer

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Landau-Kleffner Syndrome

Landau Kleffner syndrome (LKS), also called infantile acquired aphasia, acquired epileptic aphasia, or aphasia with convulsive disorder, is a rare childhood neurological syndrome characterized by the sudden or gradual development of aphasia (the inability to understand or express language) and an abnormal electroencephalogram. Discover the latest research on LKS here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.