PMID: 9420802Jul 1, 1995Paper

Gated planar technetium 99m-labeled sestamibi myocardial perfusion image inversion for quantitative scintigraphic assessment of left ventricular function

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
K A Williams, L A Taillon

Abstract

Quantitative assessment of left ventricular systolic performance in conjunction with myocardial perfusion scintigraphy would significantly expand the clinical information obtained from these studies. Left ventricular function was evaluated in 264 patients in whom planar 99mTc-labeled sestamibi myocardial perfusion images were obtained in the best septal left anterior oblique projection. Digital inversion of these perfusion images allows semiautomated evaluation of the left ventricular cavity, with the commonly available edge-detection software designed for equilibrium blood pool imaging. In this study, ejection fractions derived from this technique were compared with those obtained from a myocardial perfusion phantom, first-pass radionuclide angiography, and contrast ventriculography. In vitro validation demonstrated that the myocardial perfusion image inversion ejection fractions correlated linearly with those obtained from a double-chamber phantom (r = 0.999). In vivo, there was good linear correlation between image inversion and first-pass (r = 0.88; image inversion = 0.98 first-pass +0.11), with 95% agreement on the presence or absence of significant left ventricular systolic dysfunction. There was also very good correlatio...Continue Reading

References

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Nov 1, 1984·Journal of the American College of Cardiology·H GreenbergE M Dwyer

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Citations

Apr 7, 2005·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Kim A Williams
Feb 10, 1998·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·W H SmithD D Watson
Dec 23, 1999·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·V TodinoA Cuocolo
Dec 21, 2002·Current Cardiology Reports·Kim A Williams

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