Gel-based optical waveguides with live cell encapsulation and integrated microfluidics

Optics Letters
Aadhar JainDavid Erickson

Abstract

In this Letter, we demonstrate a biocompatible microscale optical device fabricated from agarose hydrogel that allows for encapsulation of cells inside an optical waveguide. This allows for better interaction between the light in the waveguide and biology, since it can interact with the direct optical mode rather than the evanescent field. We characterize the optical properties of the waveguide and further incorporate a microfluidic channel over the optical structure, thus developing an integrated optofluidic system fabricated entirely from agarose gel.

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Citations

Mar 29, 2014·Sensors·Simin MehrabaniAndrea M Armani
Feb 28, 2016·Micron : the International Research and Review Journal for Microscopy·Peter FloodEmmanuel G Reynaud
Jan 20, 2016·Nature Communications·Sedat NizamogluSeok Hyun Yun
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Sep 8, 2015·Scientific Reports·Lan LiJuejun Hu
Jul 6, 2012·Nanoscale·Yih-Fan ChenDavid Erickson
Oct 10, 2013·Optics Letters·Nian-Bing ZhongRong Chen
Jun 6, 2015·Advanced Materials·Myunghwan ChoiSeok-Hyun Yun
Apr 29, 2020·Scientific Reports·Eric FujiwaraCristiano M B Cordeiro
Oct 24, 2013·Optics Express·David SevrainYann Le Grand
Nov 26, 2015·Biomedical Optics Express·Matthew B ApplegateFiorenzo G Omenetto
Feb 8, 2018·SLAS Technology·Elizabeth LearyJeffrey R Morgan
Jun 13, 2018·Advanced Functional Materials·Soroush ShabahangSeok-Hyun Yun
Jul 31, 2020·Nature Reviews. Materials·Geon-Hui LeeSei Kwang Hahn
May 15, 2020·Optics Express·Anne StockhausenUlrich Kubitscheck
May 1, 2021·Advanced Materials·Carlos F GuimarãesUtkan Demirci
Jun 29, 2021·Journal of Micromechanics and Microengineering : Structures, Devices, and Systems·Zeinab RamezaniHui Fang
Sep 25, 2018·Analytical Chemistry·Jingjing GuoLingjie Kong
Apr 15, 2020·ACS Applied Materials & Interfaces·Jun FengAránzazu Del Campo

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