PMID: 11934517Apr 6, 2002Paper

Gelastic seizures and low-grade hypothalamic astrocytoma: a case report

Brain & Development
Giangennaro CoppolaRoberto Matteo Villani

Abstract

The typical, well recognized childhood epilepsy syndrome caused by hypothalamic hamartoma is characterized by early-onset, stereotyped attacks of uncontrollable laughter, frequent refractory seizures with progressive cognitive deterioration and severe behavioral problems. Here, we report a 17-year-old patient with gelastic phenomenon started in the neonatal period, later on associated with drug resistant polymorphic seizures, intellectual deficit and behavioral disorders, who improved by partial resection of an expected hypothalamic hamartoma that, in turn, resulted to be a hypothalamic low-grade astrocytoma.

Citations

May 23, 2006·Pediatric Neurosurgery·D K GuptaA K Mahapatra
Aug 4, 2009·Journal of Neurosurgery. Pediatrics·Young Seok ParkHeung Dong Kim
Oct 4, 2019·Brain and Behavior·Estefanía Conde BlancoMar Carreño

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