Geminin as a molecular target for the development of new anticancer drugs
Mini Reviews in Medicinal Chemistry
Kenichi Yoshida
Abstract
The unique biological properties of Geminin, particularly as an inhibitor of DNA replication initiation, have been recognized, and this has prompted a number of investigations into this molecule to explore its potential therapeutic as well as diagnostic usefulness. This review summarizes the possibility of Geminin serving as a new molecular target in the development of new anticancer drugs.