PMID: 15232357Jul 3, 2004Paper

Gender and irritable bowel syndrome: the male connection

Journal of Clinical Gastroenterology
Vivien MillerP J Whorwell

Abstract

Irritable bowel syndrome is more common in women; and this is generally considered to be caused by increased susceptibility. However, the opposite possibility that being male might actually protect from the disorder in some way, has largely been ignored. We have noticed that men with IBS seem to display less masculine and more feminine qualities and it was the purpose of this study to confirm or refute this clinical observation. Seventy consecutive male, secondary care outpatients fulfilling the Rome 1 criteria for irritable bowel syndrome and 70 controls completed a questionnaire to determine male and female-trait scores. In addition, all subjects were assessed using the hospital anxiety depression inventory. A highly significant reduction in male-trait scores was observed in the irritable bowel syndrome patients compared with controls (-10.5[-15.7,-5.2] P < 0.001). There were no differences between the groups with respect to female-trait scores. The prevalence of homosexuality was no different between patients and controls. Men with irritable bowel syndrome exhibit less male characteristics and it remains to be determined whether this is cause or effect. Whatever the explanation, this study adds another dimension to the role ...Continue Reading

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Citations

Jul 27, 2005·Current Gastroenterology Reports·Christine L Frissora, Kenneth L Koch
Mar 31, 2005·Journal of Clinical Gastroenterology·Brian E Lacy, Ryan De Lee
Mar 1, 2012·International Journal of Molecular Medicine·M El-SalhyT Hausken
Jun 19, 2014·International Journal of Molecular Medicine·Magdy El-SalhyTrygve Hausken
Mar 15, 2014·World Journal of Gastroenterology : WJG·Agata MulakMuriel Larauche
May 27, 2005·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·K-A Gwee
Apr 17, 2015·Nutrition Journal·Magdy El-Salhy, Doris Gundersen
Oct 24, 2018·Journal of Neurogastroenterology and Motility·Young Sun Kim, Nayoung Kim
Jul 22, 2017·International Journal of Molecular Medicine·Magdy El-SalhyDoris Gundersen
Oct 16, 2012·World Journal of Gastroenterology : WJG·Magdy El-Salhy
Nov 12, 2015·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·M PigrauC Alonso-Cotoner
May 28, 2016·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·C KnueselJ M Gschossmann
Oct 16, 2012·Scandinavian Journal of Gastroenterology·Ragnar K BreckanEyvind J Paulssen
Feb 19, 2013·Molecular Medicine Reports·Magdy El-SalhyTrygve Hausken
Aug 13, 2015·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·E R ThakurUNKNOWN Representing the IBS Outcome Study Research Group
Nov 3, 2020·Intestinal research·Michel BouchouchaRobert Benamouzig
Mar 25, 2021·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Moon Young LeeYong Sung Kim
Jun 8, 2021·Frontiers in Endocrinology·Sik Yu So, Tor C Savidge

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