Gender and lung cancer-SEER-based analysis

Annals of Epidemiology
Yaakov TolwinNir Peled

Abstract

Lung cancer remains a major cause of death worldwide. While in the past it was considered to primarily afflict males, in recent decades the number of female patients has risen, such that rates among females are similar to those among males. Nevertheless, it has been found previously (e.g., in cardiovascular disease) that when there is a sex-specific stereotype to a disease, it may remain entrenched in medical diagnostic processes, so as to cause belated diagnosis among the other sex. Gender-based differences in incidence and diagnosis are likely to exist with respect to lung cancer because of smoking habits and stereotypes, geographic and socioeconomic differences, and past epidemiologic differences between the sexes. Here we aim to characterize the effects of gender on lung cancer diagnosis and whether such effects have changed over time. The SEER (Statistics, Epidemiology, and End Results) database was used to check for sex-based differences by tumor type and stage at diagnosis and to investigate whether these patterns have changed with time by comparing staging data in different age cohorts over time. Results were stratified by location and analyzed with data regarding possible confounders such as smoking and socioeconomic f...Continue Reading

Citations

Jul 24, 2021·Journal of Clinical Laboratory Analysis·Lihuan XuBaosong Xie
Aug 12, 2021·Ear, Nose, & Throat Journal·Zhi-Min ZhangZhu-Xiang Chen
Feb 1, 2022·Therapeutic Advances in Respiratory Disease·Juan Esteban Garcia-RobledoAndrés F Cardona

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