Gender and puberty interact on the stress-induced activation of parvocellular neurosecretory neurons and corticotropin-releasing hormone messenger ribonucleic acid expression in the rat

Endocrinology
Victor ViauMargaret Wong

Abstract

Individual variations in hypothalamic-pituitary-adrenal (HPA) function are most evident at or beyond the time of puberty, when marked changes in sex steroid release occur. To explore the nature by which gender differences in HPA function emerge we examined in prepubertal (approximately 30-d-old) and postpubertal (approximately 60-d-old) male and female rats HPA activity under basal conditions and in response to 30 min of restraint. Within the ACTH-regulating, medial parvocellular portion of the paraventricular nucleus, restraint-induced Fos protein and arginine vasopressin heteronuclear RNA were lower in 60- than in 30-d-old males. No such age-related shift in the response of these synaptic and transcriptional markers of cellular activation occurred in female rats. Basal CRH mRNA expression levels in the paraventricular nucleus increased with age in female but not male rats. Conversely, only male rats showed an age-related increase in basal CRH mRNA in the central amygdala, suggesting that neuronal and neurosecretory CRH-expressing cell types are subject to different pubertal and gender influences. We conclude that gonadal regulation of the HPA axis develops via distinct mechanisms in males and females. Puberty-related shifts i...Continue Reading

References

Nov 20, 1978·Life Sciences·J A Ramaley
Jan 1, 1976·Reviews of Physiology, Biochemistry and Pharmacology·W Wuttke
Jan 1, 1988·Advances in Experimental Medicine and Biology·E J SusmanG P Chrousos
May 1, 1974·Life Sciences·J A Ramaley
May 1, 1973·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·G A Kinson, C C Liu
Oct 29, 1993·Annals of the New York Academy of Sciences·R M Liptrap
Feb 1, 1997·Seminars in Reproductive Endocrinology·L D Dorn, G P Chrousos
Jun 13, 1998·Brain Research. Developmental Brain Research·C M McCormickS M Donohue
Dec 17, 1998·Psychoneuroendocrinology·D M Vázquez
Oct 20, 1999·Current Opinion in Obstetrics & Gynecology·J Rieder, S M Coupey
May 19, 2000·Neuroscience and Biobehavioral Reviews·L P Spear
May 29, 2000·The International Journal of Neuroscience·G J Halpern, B E O'Connell
Dec 22, 2000·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·F Gomez, M F Dallman
Jun 20, 2002·Endocrinology·Helmer F FigueiredoJames P Herman
Aug 21, 2002·Stress : the International Journal on the Biology of Stress·Victoria Luine
Nov 26, 2002·Endocrinology·Jon E Levine
Feb 26, 2003·European Journal of Pharmacology·David L WalkerMichael Davis
Mar 22, 2003·Hormone Research·Evangelia CharmandariGeorge P Chrousos
May 2, 2003·Annals of the New York Academy of Sciences·Anantha ShekharDonald G Rainnie
Oct 31, 2003·Neurochemical Research·Robert M Sapolsky
Nov 8, 2003·Psychoneuroendocrinology·Clare NethertonJoe Herbert
Nov 26, 2003·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·George F Koob

❮ Previous
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Citations

Apr 11, 2012·Cellular and Molecular Neurobiology·Debra A Bangasser, Rita J Valentino
May 21, 2013·Neuropharmacology·Laura E O'Dell, Oscar V Torres
Jan 16, 2009·Development and Psychopathology·Laura R StroudRaymond Niaura
May 20, 2006·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Matthew N HillBoris B Gorzalka
Mar 10, 2011·Endocrinology·Nirupa GoelTracy L Bale
Jul 13, 2011·The Journal of Endocrinology·Allison R FoilbRussell D Romeo
Nov 20, 2013·Frontiers in Neuroendocrinology·Robert J Handa, Michael J Weiser
Dec 29, 2013·Psychopharmacology·Andrew R Burke, Klaus A Miczek
Mar 19, 2014·Psychoneuroendocrinology·Russell D RomeoIlia N Karatsoreos
Jun 9, 2007·Proceedings of the National Academy of Sciences of the United States of America·Melissa M HolmesNancy G Forger
Mar 8, 2013·Hormones and Behavior·Zoe A Klein, Russell D Romeo
Mar 13, 2014·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Travis E HodgesCheryl M McCormick
Jan 8, 2011·Reproduction, Fertility, and Development·Jacqueline M WallaceRaymond P Aitken
Jun 12, 2010·Stress : the International Journal on the Biology of Stress·J H SliwowskaL A M Galea
Apr 25, 2007·Stress : the International Journal on the Biology of Stress·Russell D RomeoBruce S McEwen
Feb 7, 2016·General and Comparative Endocrinology·Matthew R Green, Cheryl M McCormick
Nov 19, 2013·Neuroscience·K E MorrisonT L Bale
Jan 23, 2016·Frontiers in Neuroendocrinology·Nancy G ForgerAlexandra Castillo-Ruiz
Jun 26, 2012·Physiology & Behavior·Patina LuiRussell D Romeo
Apr 2, 2011·Physiology & Behavior·Jaidee K ZavalaKristin L Gosselink
Dec 15, 2010·Neuroscience and Biobehavioral Reviews·Marco Del GiudiceElizabeth A Shirtcliff
Mar 3, 2010·Frontiers in Neuroendocrinology·Russell D Romeo
Sep 29, 2009·Progress in Neuro-psychopharmacology & Biological Psychiatry·Cheryl M McCormick, Iva Z Mathews
Apr 7, 2009·Physiology & Behavior·Tamara L Doremus-FitzwaterLinda P Spear
Dec 17, 2015·Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews·Se-Jung ParkMihi Yang

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