Gender differences in adult congenital heart disease.

Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation
P Engelfriet, B J M Mulder

Abstract

Objective. To assess gender differences in morbidity, mortality and patient management among adults born with a heart defect.Methods and results. The database of the European Heart Survey on adult congenital heart disease was explored. This contains data on 4110 patients with one of eight congenital heart defects followed retrospectively for a median of 5.1 years. The existence of gender differences was assessed by considering mortality and a few 'overall' measures of morbidity. Adjusting for type of defect and age, it was found that cumulative mortality was greater in the male population (hazard ratio 1.63 (95% CI 1.12 to 2.38); p=0.011)). A significantly greater proportion of females had functional limitations (NYHA functional class >1; 37% vs. 29% of men; p=0.003). However, males were more likely to be on chronic medication during follow-up (59% vs. 55% of women; p=0.001), and males underwent diagnostic procedures more frequently (1.58/patient-year vs. 1.48/patient-year for women; p<0.02). There was no significant difference in the proportions of patients who underwent at least one intervention during follow-up, and rates of outpatient (re-)visits were not different between the sexes.Conclusion. This exploratory assessment o...Continue Reading

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Citations

Dec 12, 2012·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·B J M Mulder
Jan 25, 2013·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·E E van der Wall
Jul 21, 2012·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·E E van der Wall
Oct 25, 2011·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·E E van der Wall
Nov 6, 2012·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·E E van der Wall
Dec 2, 2009·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·P Engelfriet, B J M Mulder
Jan 5, 2010·International Journal of Cardiology·Patrick H GibsonStephen J Leslie
Nov 5, 2011·International Journal of Cardiology·Malin BerghammerMikael Dellborg
May 7, 2013·Journal of the American College of Cardiology·A Carla ZomerAriane J Marelli
Apr 23, 2013·International Journal of Cardiology·A C ZomerB J M Mulder
Feb 5, 2015·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Susanne Hwiid KlausenPhilip Moons
Apr 18, 2015·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·Joey M KuijpersBerto J Bouma
Feb 21, 2013·Journal of Cardiovascular Medicine·Giuseppe MercuroMarco Bonvicini
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Oct 18, 2013·Circulation. Cardiovascular Imaging·Samir SarikouchUNKNOWN Investigators of the German Competence Network for Congenital Heart Defects
May 1, 2019·Journal of Medical Economics·Vivian W Y LeeFranco W T Cheng
Aug 12, 2020·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·B J BoumaB J Mulder
Aug 30, 2020·European Heart Journal·Helmut BaumgartnerUNKNOWN ESC Scientific Document Group
May 31, 2020·The International Journal of Cardiovascular Imaging·Quint A J HagdornTineke P Willems
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