Gender differences in insulin and C-peptide concentrations at birth using cord blood collection

Archives of Endocrinology and Metabolism
Mohammad Shafi KuchayMohammad Ashraf Ganie

Abstract

To study gender differences in insulin and C-peptide concentrations at birth using cord blood collection. This study was conducted in a maternity hospital, in Jammu province of Jammu and Kashmir, India. All women with pregnancy who were hospitalized for delivery were followed. All pregnant ladies who had no medical condition affecting insulin levels, as per history and routine antenatal blood testing, were included in the study. The test for cord plasma insulin and C-peptide was done in 60 (30 males) full-term (≥ 37 completed weeks) normal delivery babies within 4 hours of the collection of samples using the electro-chemiluminescence immunoassay (ECLIA) on Roche elecsys module immunoassay analyzer. Weight of the babies was taken immediately after birth using digital scales. Cord plasma insulin and C-peptide measured in EDTA were compared between boys and girls and also related to birth weight. Girls were lighter (2,830 ± 37 vs. 3,236 ± 46 g; p = < 0.001) but had higher cord insulin (16.48 ± 4.88 vs. 10.53 ± 4.04 µU/mL; p = < 0.001), and C-peptide (2.47 ± 0.66 vs. 0.834 ± 0.26 ng/mL; p = < 0.001) concentrations than newborn boys. Female newborn babies have higher cord plasma insulin and C-peptide concentrations than male newborn...Continue Reading

References

Jan 1, 1995·The Journal of Clinical Endocrinology and Metabolism·S H TraversR H Eckel
Apr 8, 2003·The Journal of Clinical Endocrinology and Metabolism·R S LindsayUNKNOWN Scottish Multicentre Study of Diabetes in Pregnancy
Apr 21, 2005·The Journal of Clinical Endocrinology and Metabolism·Sarah EhtishamTimothy Barrett
Jun 28, 2006·International Journal of Obesity : Journal of the International Association for the Study of Obesity·T J Wilkin, M J Murphy

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Citations

Mar 6, 2019·American Journal of Epidemiology·Zhenqiu LiuXingdong Chen
Jan 17, 2021·Life·Ilaria CampesiGiampiero Capobianco

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