Gender differences in mortality, quality of life and function after restorative procedures for rectal cancer

Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland
M ZutshiJ Hammel

Abstract

Studies investigating the functional outcome after restorative surgery for rectal cancer have mainly focused on the effect of different surgical techniques on bowel habit or sexual activity at a single time-point. The aim of this study was to assess, longitudinally, the effect of rectal cancer treatment on bowel function, quality of life and sexual activity. The study parameters were assessed using self-administered questionnaires, including the Short Form 36 (SF-36), repeatedly, over a 5-year period. Patient details were obtained from the Cleveland Clinic prospective database. There were 260 (186 male) patients. The mean ages of male and female patients at the time of surgery were 60.5 and 57.5 years, respectively. There was no significant difference in comorbidity or stage between the groups. Women had a better overall survival. More women than men had postoperative radiation and perioperative blood transfusions. Men had a higher percentage of hand-sewn anastomoses (23.9%vs 10.8%, P = 0.018), but there was no overall difference in the mean level of anastomosis (2.3 cm vs 1.9 cm, P = 0.38). Men had worse nocturnal bowel function, more incontinence and a poorer mental component score on the SF-36. Pad use increased over time to...Continue Reading

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Citations

Apr 24, 2013·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Maria I LapidTeresa A Rummans
Jun 27, 2012·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·M M Lange, C J H van de Velde
Dec 18, 2013·Seminars in Oncology·Charles W Given, Barbara A Given
Nov 26, 2013·Surgical Oncology Clinics of North America·Daniel Fish, Larissa K Temple
Nov 5, 2016·Psycho-oncology·Catherine E MosherBert H O'Neil
Apr 16, 2016·Journal of Clinical Nursing·Show-Ing ShiehHong-Yu Tung
Nov 10, 2013·Diseases of the Colon and Rectum·Myung Mi ChoKevork Kazanjian
Dec 17, 2014·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·M-L Lydrup, P Höglund
Jun 22, 2020·International Journal of Colorectal Disease·Feng BaoZhigang Deng

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