Gender Differences in Patients with Takotsubo Cardiomyopathy: Multi-Center Registry from Tokyo CCU Network

PloS One
Tsutomu MurakamiMorimasa Takayama

Abstract

The clinical features of gender differences in takotsubo cardiomyopathy (TC) remain to be determined. The aim of this study was to evaluate the differences in clinical characteristics of male and female patients with TC. We obtained the clinical information of 368 patients diagnosed with TC (84 male, 284 female) from the Tokyo CCU Network database collected from 1 January 2010 to 31 December 2012; the Network is comprised of 71 cardiovascular centers in the Tokyo (Japan) metropolitan area. We attempted to characterize clinical differences during hospitalization, comparing male and female patients with TC. There were no significant differences in apical ballooning type, median echocardiography ejection fraction, serious ventricular arrhythmias (such as ventricular tachycardia or fibrillation), or cardiovascular death between male and female patients. Male patients were younger than female patients (median age at hospitalization for male patients was 72 years vs. 76 years for female patients; p = 0.040). Prior physical stress was more common in male than female patients (50.0% vs.31.3%; p = 0.002), while emotional stress was more common in female patients (19.0% vs. 31.0%; p = 0.039). Severe pump failure (defined as Killip Class ...Continue Reading

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Citations

Jun 9, 2017·European Heart Journal. Acute Cardiovascular Care·Kaoru AndoYo Koyama
Mar 7, 2017·International Journal of Cardiology·Yoshihiro SobueYukio Ozaki
Feb 28, 2018·Clinical Cardiology·Evann EisenbergIleana L Piña
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Dec 17, 2019·European Journal of Heart Failure·Felice Lin, Barry Greenberg
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Sep 25, 2019·Journal of Women's Health·Arianne Clare AgdamagAnnabelle Santos Volgman
Apr 27, 2018·Heart and Vessels·Ken KatoYoshio Kobayashi
Mar 19, 2021·Cardiovascular Research·Saraschandra VallabhajosyulaVirginia M Miller
Apr 25, 2020·Journal of the American College of Cardiology·Victoria L CammannChristian Templin
Aug 11, 2021·ESC Heart Failure·Xiaojia LuBin Wang

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Methods Mentioned

BETA
biopsy

Software Mentioned

JMP

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