Abstract
The female gender has been shown as high-risk factor for mortality and morbidity. We sought to assess the influence of female gender on coronary artery bypass graft (CABG) surgery from our own experience. This is a retrospective analysis of prospectively collected database from a single centre. Patients were grouped according to gender and potential differences in pre-operative, intra-operative and post-operative factors were explored. Significant high-risk factors were then fitted in a multivariate model to account for differences in predicting gender influence on surgical outcomes. Two thousand eight hundred and four consecutive patients underwent isolated first-time CABG between February 2000 and December 2008; 562 (20%) patients were females. Pre-operatively, females were more likely to have significant comorbidities (age, congestive cardiac failure, hypercholesterolemia, hypertension, ischemic heart disease, peripheral vascular disease, pre-op arrhythmias, small body surface area and poor ejection fraction (p < 0.001)) consistent with higher Euroscore (p > 0.0001) and more urgent surgery (p < 0.002). Intra-operatively, they showed less extent pattern of disease requiring less bypass and cross-clamp time (p < 0.001). Observ...Continue Reading
References
Aug 14, 1991·JAMA : the Journal of the American Medical Association·G T O'ConnorL Adrian
Apr 15, 1990·Annals of Internal Medicine·S S KhanJ Matloff
Jan 1, 1985·Circulation·M J CowleyE R Passamani
Jul 1, 1987·Annals of Internal Medicine·J N TobinJ Wachspress
Jun 1, 1985·Annals of Surgery·T J GardnerB A Reitz
Feb 1, 1983·Journal of the American College of Cardiology·F D LoopW C Sheldon
Nov 1, 1995·The Journal of Thoracic and Cardiovascular Surgery·G T ChristakisT E David
Nov 1, 1995·Circulation·L L MickleboroughS Mohamed
Aug 15, 1995·Circulation·Y LiaoD L McGee
Nov 1, 1993·Circulation·G T O'ConnorD J Malenka
Jan 1, 1993·Journal of the American College of Cardiology·S H RahimtoolaA Starr
Mar 17, 1999·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·J BellchambersJ R Pepper
Jul 10, 1999·Journal of the American College of Cardiology·E O WeinbergB H Lorell
Jul 22, 1999·The New England Journal of Medicine·L F Wexler
Mar 31, 2000·American Heart Journal·S E SheiferN J Weissman
Oct 4, 2000·The Annals of Thoracic Surgery·D AbramovS E Fremes
Oct 12, 2000·JAMA : the Journal of the American Medical Association·J MehilliA Schömig
May 23, 2001·Circulation·C W HogueV G Dávila-Román
Mar 13, 2002·Circulation·Viola VaccarinoWilliam S Weintraub
Aug 15, 2002·American Heart Journal·Warren J CantorE Magnus Ohman
Mar 22, 2003·Journal of the American College of Surgeons·Scott E WoodsKim Hasselfeld
Oct 21, 2003·The Journal of Thoracic and Cardiovascular Surgery·Lynda L MickleboroughJoan Ivanov
Dec 21, 2004·Journal of the American College of Cardiology·Vera Regitz-ZagrosekRoland Hetzer
Mar 9, 2006·European Heart Journal·Marco Stramba-BadialeMichal Tendera
May 13, 2011·Journal of Public Health·Peter ScarboroughMike Rayner
Apr 12, 2012·European Journal of Clinical Nutrition·P ScarboroughM Rayner
Citations
Feb 24, 2015·International Journal of Surgery·Shahzad G RajaJulian W E Jarman
Dec 12, 2013·The American Journal of Cardiology·Rasha Al-LameeGhada W Mikhail
Jan 1, 2014·Transfusion·Alexander B A VonkChrista Boer
Apr 29, 2014·The Journal of Thoracic and Cardiovascular Surgery·Felix GirrbachFriedrich-Wilhelm Mohr
Nov 19, 2015·Cardiovascular Engineering and Technology·Shirin Masjedi, Zannatul Ferdous
Oct 11, 2012·International Journal of Cardiology·Waleed T KayaniSalim S Virani
Jan 19, 2015·The American Journal of Cardiology·Benjamin PollockGiovanni Filardo
Jul 7, 2016·The American Journal of Cardiology·Kimberly A SkeldingJeffrey J Popma
Oct 8, 2016·Journal of Cardiothoracic Surgery·Francesco NicoliniUNKNOWN RERIC (Registro dell’Emilia Romagna degli Interventi Cardiochirurgici) Investigators
Feb 6, 2016·PloS One·Rawa ArifCarsten J Beller
Oct 21, 2016·Circulation. Cardiovascular Quality and Outcomes·Giovanni FilardoRalph Damiano
Jun 9, 2017·PloS One·Gulinu MaimaituxunMasataka Sata
Jul 3, 2020·Journal of Cardiothoracic Surgery·Anthony LemaireLeonard Y Lee
Jul 29, 2020·Journal of Cardiac Surgery·Mario GaudinoUmberto Benedetto
Jan 17, 2021·World Journal of Surgery·Byron L CrapeKarapet Davtyan
Oct 29, 2020·Annals of Cardiac Anaesthesia·Feridoun Sabzi, Atefeh Asadmobini
Dec 15, 2020·Journal of Cardiac Surgery·Dmitry PevniYanai Ben-Gal
Jul 22, 2021·Seminars in Thoracic and Cardiovascular Surgery·Eilon RamEhud Raanani
Sep 4, 2021·Interactive Cardiovascular and Thoracic Surgery·N Bryce RobinsonMario Gaudino