Abstract
Although male predominance was documented in previous studies on cryptococcal meningoencephalitis (CM), there has been no statistical study about female CM patients despite recently noticeable increase in female prevalence. In the current study, we aimed to investigate the independent gender-specific contributing risk factors for onset of CM and factors related to survival time in female patients by chosen statistical tools. There have been 108 patients diagnosed with CM from July 1, 1998 to June 30, 2013 in Nanfang Hospital that were included in our study. This 15-year retrospective study compared demographic and clinical features of 31 female patients with 77 males. Multivariate analysis was performed for detection of the contributors to the onset of CM in female patients. The independent variables for multivariate analysis were selected according to statistical significance in univariate analysis. Furthermore, Cox regression model was used to evaluate the factors related to survival length. Use of corticosteroids or other immunosuppressants (32.3 % versus 11.7 %; p = 0.011) and history of systemic lupus erythematosus (SLE) and other autoimmune diseases (29 % versus 3.9 %; p < 0.001) were more common in females, but only the ...Continue Reading
References
Feb 10, 2000·Arquivos de neuro-psiquiatria·C DarzéA Melo
Dec 17, 2004·Mycoses·K TintelnotA Polak
Mar 4, 2005·Mycoses·Gary D FriedmanLeo B Hurley
Jul 5, 2005·General Hospital Psychiatry·Wai Kwong TangC M Leung
Jul 25, 2006·Infection and Immunity·Dennis M LindellGary B Huffnagle
Jul 11, 2007·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Robert M Kwee, Thomas C Kwee
Feb 2, 2008·The British Journal of Radiology·F VawdaK Naidoo
Jul 25, 2009·Mycoses·S T TayH Hamimah
Nov 7, 2009·Revista Do Instituto De Medicina Tropical De São Paulo·Maria Laura Botelho CostaJoão Luiz Pinto E Silva
Apr 14, 2010·Neurology·Jennifer Bestard, Zaeem A Siddiqi
May 4, 2010·Gender Medicine·Marianne J Legato
Feb 2, 2011·Neuroepidemiology·Yen-Yu Chen, Chien-Hsu Lai
Feb 15, 2011·Journal of the International Association of Physicians in AIDS Care : JIAPAC·Seema U NayakMayurika Ghosh
Oct 8, 2011·Mycopathologia·Chen YuchongZheng Zhizhong
Dec 2, 2011·Mycopathologia·Delio José MoraMario León Silva-Vergara
Dec 27, 2012·BMC Infectious Diseases·Jianhua GuoShunxiang Qi
Mar 5, 2013·PloS One·Vasilios PyrgosPeter R Williamson
Apr 30, 2013·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Denisse Vázquez-GonzálezAlexandro Bonifaz
Sep 5, 2013·Journal of the International Association of Providers of AIDS Care·Candice K KwanPaul J Weidle
Sep 21, 2013·Annual Review of Pathology·Carolina CoelhoArturo Casadevall
May 30, 2014·Clinical Epidemiology·Derek J Sloan, Victoria Parris
Mar 25, 2015·Lupus·D ComteG C Tsokos
Apr 19, 2015·BMC Infectious Diseases·Hui ZhengQun Wang