Gender-specificities in Alzheimer's disease and mild cognitive impairment.

Journal of Neurology
U BeinhoffM W Riepe

Abstract

Amnestic Mild Cognitive Impairment (MCI) is a condition with an increased risk for developing Alzheimer's disease (AD). Presently, gender differences are neglected in the assessment of MCI and AD. We examined verbal and visuospatial episodic memory in 143 subjects diagnosed as healthy controls (HC; N = 48, Mini-Mental State Examination (MMSE) 29.2 +/- 1.0 (mean +/- standard deviation)), MCI (N = 43,MMSE 28.5 +/- 1.4), and AD (N = 49, MMSE 25.1 +/- 2.2). Female HC and MCI subjects performed better on verbal episodic memory tasks than males. In contrast, visuospatial episodic memory was better in male than female AD patients. We interpret the results in light of a gender-specific cognitive reserve and conclude that the gender-specificity of neuropsychological performance needs to be accounted for in clinical diagnosis of Alzheimer's disease.

References

Nov 1, 1975·Journal of Psychiatric Research·M F FolsteinP R McHugh
May 1, 1988·Journal of Clinical Psychology·M L BleeckerD A Meyers
Jan 1, 1994·Neurology·V W Henderson, J G Buckwalter
Jan 9, 1998·Memory & Cognition·A HerlitzL Bäckman
Feb 5, 1999·Neurology·H BuschkeR B Lipton
Feb 13, 1999·Journal of the American Geriatrics Society·E Barrett-Connor, D Kritz-Silverstein
Apr 6, 1999·Archives of Neurology·R C PetersenE Kokmen
Sep 15, 1999·Alzheimer Disease and Associated Disorders·K A BaylesE B Montgomery
Nov 15, 2000·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·L E HebertD A Evans
Jan 3, 2001·Brain : a Journal of Neurology·L BäckmanL Fratiglioni
Jul 28, 2001·International Psychogeriatrics·S McPhersonJ L Cummings
Dec 26, 2001·Archives of Neurology·R C PetersenB Winblad
Apr 10, 2002·Journal of the International Neuropsychological Society : JINS·Yaakov Stern
Dec 21, 2002·Lancet·Alistair Burns, Michael Zaudig
Feb 1, 2003·BMJ : British Medical Journal·Katie PalmerLaura Fratiglioni
Feb 7, 2003·Journal of the International Neuropsychological Society : JINS·Joel H KramerDean C Delis
Feb 26, 2003·Neurobiology of Aging·Georg GrönMatthias W Riepe
Jun 11, 2003·Neurology·L L BarnesD A Bennett
Jun 25, 2003·Brain and Cognition·Julie E YonkerAgneta Herlitz
Dec 5, 2003·Gerontology·Marja J AartsenUNKNOWN Longitudinal Aging Study Amsterdam
Jan 20, 2004·Neuropsychologia·Thomas D ParsonsAlbert A Rizzo
Nov 16, 2004·Ageing Research Reviews·Lawrence J WhalleyJohn M Starr
Mar 8, 2005·Cerebral Cortex·Yaakov SternRonald van Heertum
Apr 9, 2005·Memory & Cognition·Scott B MaitlandLars-Göran Nilsson
Sep 15, 2005·Dementia and Geriatric Cognitive Disorders·Ulrike BeinhoffMatthias W Riepe

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Citations

Jul 7, 2012·PloS One·Laurence O'DwyerHarald Hampel
Jan 1, 2009·International Journal of Alzheimer's Disease·U BeinhoffM W Riepe
Aug 24, 2012·Journal of Clinical and Experimental Neuropsychology·Karen IrvineTejinder K Kondel
Mar 18, 2016·Neurology·Erin E SundermannUNKNOWN Alzheimer's Disease Neuroimaging Initiative
Feb 11, 2015·Journal of the International Neuropsychological Society : JINS·Richard J CaselliYonas E Geda
Mar 31, 2015·Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition·Julia RaheElke Kalbe
Jan 8, 2015·Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition·Michael ZhangDawson W Hedges
Oct 1, 2011·Hormone Molecular Biology and Clinical Investigation·Roberto Cosimo Melcangi, Luis M Garcia-Segura
Jan 21, 2017·Journal of Alzheimer's Disease : JAD·Erin E SundermannUNKNOWN Alzheimer’s Disease Neuroimaging Initiative
Aug 30, 2012·American Journal of Alzheimer's Disease and Other Dementias·Yi XingJianping Jia
Mar 26, 2016·World Journal of Psychiatry·Keith R LawsTim M Gale
Apr 23, 2019·Brain and Behavior·Xifan WangFei Han
May 17, 2019·Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition·Mandy RohegerElke Kalbe
Feb 15, 2020·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·M T FerrettiR Schmidt
Jan 9, 2020·Alzheimer Disease and Associated Disorders·Mohamad El HajKarim Gallouj
Jun 18, 2019·Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology·Mandy RohegerElke Kalbe
Apr 28, 2020·Brain Communications·Leonardino A DigmaUNKNOWN Alzheimer’s Disease Neuroimaging Initiative
Jul 25, 2018·Translational Neurodegeneration·Ke YangJian-Jun Wu
May 30, 2017·Dementia and Geriatric Cognitive Disorders Extra·M Rosa ElosúaMaría José Contreras
Sep 28, 2020·Brain and Behavior·Mandy RohegerClive Ballard
Jan 26, 2021·Journal of Alzheimer's Disease : JAD·Daniel Cuervo-ZanattaClaudia Perez-Cruz

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