Dec 29, 2000

Gene admixture in the silk road region of China: evidence from mtDNA and melanocortin 1 receptor polymorphism

Genes & Genetic Systems
Y-G YaoY P Zhang


Mitochondrial DNA control region segment I sequences and melanocortin 1 receptor (MC1R) gene polymorphism were examined in ethnic populations in the silk road region of China. Both the frequencies of the MC1R variants and the results of mtDNA data in this region presented intermediate values between those of Europe and East and Southeast Asia, which suggested extensive gene admixture in this area and was in general agreement with previous studies. Phylogenetic analysis of the ethnic populations in the Silk Road region that based on mtDNA data didn't show expected cluster pattern according to their ethnogenesis. We suspect that a high migration rate in female among these closely related populations and other three demographic events might account for it.

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Mentioned in this Paper

Gene Polymorphism
MC1R Protein
DNA, Mitochondrial
Hybridization, Intraspecies
Corticotropin Receptors
Melanocortin receptor
Genetic Equilibrium
Genetic Polymorphism
MC1R gene
Mitochondrial DNA Location

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