Gene Amplification: Trophoblast Giant Cells Use All the Tricks

Current Biology : CB
James C Cross

Abstract

Evolutionary gene duplication, developmental endoreduplication and selective gene amplification are alternative strategies for increasing gene copy number. When these processes occur together, things get really interesting, and new work shows that is the lifestyle of cells in the placenta.

References

May 16, 1998·Molecular Biology of the Cell·A MacAuleyZ Werb
Dec 19, 2002·Endocrinology·Dustin O WiemersMichael J Soares
Jun 22, 2006·Trends in Genetics : TIG·Donna G Albertson
Feb 10, 2007·Developmental Biology·David G SimmonsJames C Cross
Feb 28, 2007·Trends in Endocrinology and Metabolism : TEM·Michael J SoaresS M Khorshed Alam
Dec 12, 2012·Development·Donald T Fox, Robert J Duronio
May 3, 2014·PLoS Genetics·Roberta L HannibalJulie C Baker
Jan 7, 2015·Proceedings of the National Academy of Sciences of the United States of America·Annettee NakimuliAshley Moffett
Jan 18, 2016·Current Biology : CB·Roberta L Hannibal, Julie C Baker

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